Goal 2: Reduce Human Disease

Anemia, oxygen delivery, and red blood cell transfusion

In neonatal, pediatric, and adult patients with critical illness, what is the best means to identify: (1) the degree to which anemia contributes to insufficient oxygen (O2) delivery and (2) the likelihood that O2 delivery will be improved by red blood cell (RBC) transfusion?

 

These questions are most relevant to critically ill populations that exhibit unique physiology, including those with low cardiac output (cardiac failure), hypoxia (cyanotic pulmonary or heart disease), vasculopathy (cerebral or myocardial infarction) or increased metabolism (burns, sepsis).

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Idea No. 440