Goal 3: Advance Translational Research

Chronobiology in Chronic Lung Diseases

In the new era of once a day inhalers for Asthma and COPD, there is critical need to determine whether delivery of drugs to the lung at night or day have different therapeutic effects and/or side effect profile.

Tags (Keywords associated with the idea)

Is this idea a Compelling Question (CQ) or Critical Challenge (CC)? : Critical Challenge (CC)

Details on the impact of addressing this CQ or CC :

Understanding whether a delivery of a LAMA, LABA and/or ICS at different times of the day has a potential critical impact in symptom control and preservation of lung function

Feasibility and challenges of addressing this CQ or CC :

This question can ben addressed via the use of Pragmatic Clinical Trials.

Name of idea submitter and other team members who worked on this idea : Alejandro Comellas

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Idea No. 624