Goal 2: Reduce Human Disease

Embrace and fund RCTs that enroll heterogeneous samples of patients

Critical care medicine comprises a diffuse array of diseases, syndromes, illnesses and symptoms arising from those sources requiring advanced care by highly trained teams of interdisciplinary professionals. Research is sorely needed on generating evidence that is broadly applicable to a heterogeneous group of patients. This is a major challenge for researchers who enroll critically ill patients into their clinical trials. Clinical trials with critically ill patients should be funded that propose solid science but do not conform to the ‘gold standard’ double-blind RCT. Enrolling only homogeneous samples into RCTs does not always move science forward and usually does not reduce health care expenditures. Real world trials are needed in the ICU

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Idea No. 1602