Goal 2: Reduce Human Disease

Fetal basis for Adult Disease

Maternal exposures during pregnancy have the potential to alter development and lead to lifelong susceptibility to disease. There is epidemiological evidence of this in the asthma field, where maternal smoking leads to increased asthma rates. However, the molecular mechanisms by which maternal exposures cause lung disease later in life are not known and the influence of in utero exposures on susceptibility to lung cancer, COPD, IPF, and other lung diseases is unknown.

Tags (Keywords associated with the idea)

Voting

10 net votes
17 up votes
7 down votes
Active
Idea No. 748