Goal 1: Promote Human Health

Gene regulatory networks in HLB disease mechanisms

What is the level of population variation of gene regulatory networks in heart, lung, and blood and sleep disease mechanisms? Can we use different animal model strains to identify key factors in networks and modifier genes?

Tags (Keywords associated with the idea)

Is this idea a Compelling Question (CQ) or Critical Challenge (CC)? : Compelling Question (CQ)

Details on the impact of addressing this CQ or CC :

Improve our understanding of the pathophysiology of disease and perhaps identify novel targets for intervention.

Feasibility and challenges of addressing this CQ or CC :

Advances in high throughput technology have made addressing these questions possible.

Name of idea submitter and other team members who worked on this idea : NHLBI Staff

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Idea No. 4