How do we harness the ongoing “natural experiments” of quality improvement (QI) activities in various healthcare systems to facilitate hypothesis-driven research, improve scientific validity to address questions in clinical trials, and implement and disseminate research results?
• Current restrictions in human subjects research regulations
• Diversity in approaches and methodology rigor to QI initiatives across different health systems
• The discipline is not well regarded in academia
• Difficulty in creating a culture of QI in a business-like healthcare environment