Goal 2: Reduce Human Disease

Identifying the High Venous Thromboembolism-Risk Individual

Over 500,000 incident or recurrent venous thromboembolism (VTE) events occur annually in the US. Almost one-quarter of acute pulmonary embolism patients suffer sudden death. To improve survival, the occurrence of VTE must be reduced. However, the incidence of VTE has increased over the last 30 years. Moreover, near universal prophylaxis of patients hospitalized for surgery or for medical illness has not reduced hospitalization-associated VTE attack rates. This failure is due to our inability to identify the high VTE-risk individual and target risk factor modification and/or intensive prophylaxis to the individual who would benefit most.

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Idea No. 301