Goal 2: Reduce Human Disease

Improving the Detection and Treatment of Cardiac Sarcoidosis

Sarcoidosis afflicts young adults, particularly African Americans and females, and often causes chronic disability or death. Cardiac sarcoidosis (CS) was once considered to be a rare disease manifestation; however, with the development of improved diagnostic testing procedures, such as MRI and PET scans, CS is now known to afflict up to 40% of sarcoidosis patients and is recognized as a major cause of death. The current AHA guidelines recommend automated defibrillator (AICD) placement in all CS patients, but this is impractical (too expensive, and not necessary in most cases), and the role of immunomodulating treatments for CS is also unclear. There is a pressing need to improve CS detection and to standardize treatment for CS

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Idea No. 819