Management of COPD in the presence of comorbidity
• Does a protocol-based screening for commonly occurring comorbid conditions in patients with COPD (eg. CAD, CHF, depression, sleep apnea) improve management and outcomes for patients with COPD?
• How should providers coordinate management strategies and treatment goals in patients with COPD and other co-existing chronic diseases?
• What is the comparative effectiveness and safety of guideline-recommended COPD care in patients with ‘few’ vs. ‘many’ clinically significant (e.g., depression, sleep disorder, cardiovascular) comorbidities?
• What should be the clinical endpoints in frail elderly vs. other patients with COPD when titrating COPD care?