Goal 2: Reduce Human Disease

Mechanism and target identification for cardiovascular disease using database mining and experimental strategies

The big database of -omics and noncoding RNAs provide a valuable search engine to establish the link of various disease conditions with pathways and molecules. During recent year, data mining of available biomedical data and information has merged for target discovery and mechanism identification. However, current database mining research remains limited and largely hypothetical. Comprehensive research using the combinatory approaches including database mining on multiple databases and dissecting the underlying mechanism experimentally is in great needs. We suggest NHLBI increasing support on research using the combination of database mining and experimental strategies to identify novel mechanism and target for cardiovascular disease.

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Idea No. 827