Goal 2: Reduce Human Disease

Spirometry for diagnosis and treatment of COPD

1. What is the comparative effectiveness of different approaches to implementing use of spirometry in primary care to confirm the diagnosis of COPD (e.g., increased reimbursements, use of EMRs and other tools)

2. What is the comparative effectiveness of using symptoms vs. spirometry in increasing patient and adherence to COPD treatment guidelines?

3. What is the comparative effectiveness of using a fixed FEV1/FVC ratio vs. an age-adjusted FEV1/FVC ratio in increasing the accuracy of COPD diagnosis?

4. What is the comparative effectiveness of early identification and treatment of GOLD Stages 1-2 COPD through the use of screening spirometry in high risk populations vs. usual care in these populations on improve patient-reported outcomes?

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Idea No. 1596