Goal 2: Reduce Human Disease

Study on key product factors for optimal Bone Marrow Transplantation (BMT) graft function

Hematopoietic progenitor cells (HPC) collected by Apheresis is the most common source used for BMT. How the cells are collected and what kinds of cells are collected can affect BMT graft function. Limited studies have been done to study the key product factors in relationship to optimal graft function.

Questions remain such as the optimal lymphocytes contents for reduced infection post BMT, optimal megakaryocyte precursor for platelet engraftment, reduced tumor contamination for reducing disease recurrence, and balanced lymphocyte contents for preventing graft versus host disease, etc.

Tags (Keywords associated with the idea)


70 net votes
93 up votes
23 down votes
Idea No. 729