Is this idea a Compelling Question (CQ) or Critical Challenge (CC)?
Compelling Question (CQ)
Details on the impact of addressing this CQ or CC
HFPEF is as serious as HFREF and as many forms of cancer. But there is no therapy. Generic neurohormonal antagonist drugs are effective in HFREF and have potential in HFPEF. They will not be studied by industry and trials need public funding.
Feasibility and challenges of addressing this CQ or CC
The challenge is streamlined efficient trials. This can be addressed with the registry-randomized trial concept.
Name of idea submitter and other team members who worked on this idea
Lars H. Lund