Goal 4: Develop Workforce and Resources

Training in Small Molecule Discovery and Development

The current generation of heart,lung, and blood investigators are not equipped with competitive training needed to approach, design, and test appropriately small molecule therapeutics that may move through the FDA pipeline. Appropriate in silico ligan or structure based design, HTS, design of Pd/Pk models, "go-no-go" branchpoints in drug development, screening approaches, and drug target validation are issues that are not taught formally to trainees and faculty. In addition, issues such as IP, FTO landscape analysis, regulatory policies, FDA milestones, and product development and marketing are almost nonexistent.

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Idea No. 600