Goal 2: Reduce Human Disease

What new methods of platelet preparation, processing, and storage are needed for hemostasis in various clinical conditions?

The limitations of 5-day 22˚ C storage significantly impacts platelet availability. It is critical that we develop new methods of collection, processing, storage to extend the storage time of platelets, and evaluate the use of whole blood. The attributes of these products must be understood to optimally alignment product attributes, clinical efficacy and safety with hemostatic needs in a variety of clinical states. Specifically, what measurable characteristics of these products and their effects in the recipient can be used to maximize safety and efficacy? In what clinical situations are different platelet components most effective? What laboratory tests, including point of care, could guide platelet transfusion therapy?

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Idea No. 434