Goal 3: Advance Translational Research

Xenotransplantation is the future and ideal treatment for end stage organ failure

A genetically engineered and humanized pig organ expressing human genes and devoid of antigens immunogenic to humans may prove to be an ideal solution to overcome the acute organ shortage for solid organ transplantation. Recently, a remarkable progress has been made in this direction with reports of graft survival approaching 3 yrs in a pig to primate cardiac transplantation model.The issues of viral transmission and ethical restrictions are also being adequately addressed . This solution appears to be much closer than other valid options available for organ shortage. Therefore, we submit that recent progress in this field is worth appreciation and support.

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Idea No. 602