Goal 2: Reduce Human Disease

National AICD and resynchronization therapy prospective registry

Emerging data suggest underutilization and variation of care in heart failure patients with ICD defibrillator therapy. Furthermore, there is a lack of data about those who benefit and those who will not benefit, including the role of gender, age and CHF morphology (phenotype).


creation of reliable and validated data entered into a registry with cases and controls

Tags (Keywords associated with the idea)

Is this idea a Compelling Question (CQ) or Critical Challenge (CC)? : Critical Challenge (CC)

Details on the impact of addressing this CQ or CC :

identifying (bio)markers for improving selection of the best suitable population to receive the max benefit, and avoid utilization of ineffective and very costly strategies for those with minimal benefit.

Feasibility and challenges of addressing this CQ or CC :

Heart failure is one of the few cardiovascular disease that continues to increase, and with the aging population and better MI management and cardiovascular disease clinical trials, there is an increasing evidence of the importance of assessment of patients who benefit the most. The challenge with current various registries is a lack of QC/QA data. Having a reliable registry would facilitate identification of high risk patients who would most likely benefit from the AICD/RST and those who would not benefit from these interventions.

Name of idea submitter and other team members who worked on this idea : NHLBI Staff


-9 net votes
3 up votes
12 down votes
Idea No. 209