Goal 2: Reduce Human Disease

The 'other' circulation system - the lymphatic system needs the attention the blood circulation system receives.

Much is still unknown about the lymphatic system. No medical specialist owns it. NHLBI and NCI could work together on understanding lymphatic disease in the direction of understanding how metastasis spreads disease. NHLBI can help by establishing a unit to organize research interest in such an important body system in health and disease.

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Is this idea a Compelling Question (CQ) or Critical Challenge (CC)? : Critical Challenge (CC)

Details on the impact of addressing this CQ or CC :

Understanding the lymphatic system and how metastasis facilitates it as a highway to spread disease could save many lives.

Feasibility and challenges of addressing this CQ or CC :

There are several lymphatic diseases such as lymphangiomatosis - which are complex and systemic - through the study of which, we can learn the role the lymphatic system plays in disease - beyond the well-known essential functions of fat absorption, the immune response and in maintaining fluid balance.

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Idea No. 1123