(@alexandercan.aw)

Goal 2: Reduce Human Disease

Condom with Retention Means And Shield (Patent Pending)

Condom designed to protect a males pubic areas and scrotum, fingers and hands from coming in contact with infectious fluids. The adoption of a shield to reduce the occurrence of HPV and other STI infections. This is the first and only condom in the world that uses a latex shield which is designed to protect a promiscuous males fingers and hands from HPV and other infectious human secretions that may be in fluids,. We... more »

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-43 net votes
1 up votes
44 down votes
Active
(@grang001)

Goal 3: Advance Translational Research

Preventing Stroke from Atrial Fibrillation

How can health systems develop and implement validated measurement and feedback tools to identify patients with atrial fibrillation, categorize their risk factors for stroke, capture reasons for non-treatment, and develop interventions customized to those reasons to substantially improve the proportion of patients receiving effective oral anticoagulant stroke prevention treatment?

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6 net votes
8 up votes
2 down votes
Active
(@danacpeters)

Goal 2: Reduce Human Disease

5-minute MRI exam

MRI is a lengthy and expensive exam, but this is mainly because it has no ionizing radiation and is uniquely safe and uniquely versatile, leading to imaging sessions that last for 1/2 to 1 and 1/2 hours, with multiple scans, views and contrasts. MRI could provide better quality screening scans, compared to x-ray, ct or echo, in 5 minutes, without ecg-gating and lengthy preparation of the patient. However, the optimal... more »

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0 net votes
1 up votes
1 down votes
Active
(@katherinek)

Goal 2: Reduce Human Disease

How can we non-invasively, but still accurately, measure blood pressure in the pulmonary arteries?

Pulmonary hypertension (PH) is a complex, progressive condition characterized by high blood pressure in the lungs. The gold standard for measuring pressures in the pulmonary arteries is a right heart catheterization, where a special catheter is guided through the right side of the heart and into the pulmonary artery, the main vessel carrying blood to the lungs. This measurement is essential, as it allows physicians and... more »

Voting

67 net votes
75 up votes
8 down votes
Active
(@kullerl)

Goal 2: Reduce Human Disease

What is the Relationship Between CVD and Dementia in the Elderly?

The successes of preventing and treating CHD, CVD has resulted in a substantial increase in life expectancy, a very important success story, but unfortunately it has led to a growing population of elderly 80+ years of age.

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3 net votes
21 up votes
18 down votes
Active
(@juliewashko)

Goal 2: Reduce Human Disease

Assess the true impact of sickle cell trait on cardiovascular health across then age spectrum

Sickle cell disease is now understood as a disease of inflammation in addition to abnormal red blood cells. It is likely persons with sickle cell trait are also negatively affected by the damage caused by inflammation. There is a significant racial disparity in hypertension, stroke, and chronic kidney disease. It remains unclear the degree to which sickle cell trait contributes to this disparity. It also remains unclear... more »

Voting

17 net votes
31 up votes
14 down votes
Active
(@nhlbiforumadministrator1)

Goal 3: Advance Translational Research

Arrhythmia Therapies Based on Understanding Mechanisms

There is a need to translate these new insights of genetic, molecular, cellular, and tissue arrhythmia mechanisms into the development of novel, safe, and new therapeutic interventions for the treatment and prevention of cardiac arrhythmias.

Voting

51 net votes
86 up votes
35 down votes
Active
(@nhlbiforumadministrator1)

Goal 3: Advance Translational Research

Engineering Challenges for Next Generation VADs

Critical challenges to overcome include the development of non-platelet activating impellers and hypothrombogenic surfaces in modern ventricular assist devices (VADs). Percutaneous and transcutaneous electric drive systems will need to evolve, and clinical research is needed to reduce thromboembolism and bleeding (acquired von Willebrand syndrome). Adverse events may also be further reduced if smaller pumps, for partial... more »

Voting

6 net votes
27 up votes
21 down votes
Active
(@nhlbiforumadministrator1)

Goal 2: Reduce Human Disease

US-based Clinical Development of Innovative Medical Devices

Though innovative medical devices are often conceived of and developed in the US, US consumers are frequently the last to benefit. Innovators frequently go to market first in Europe and are now moving toward emerging countries, delaying the medical benefits available to the US population. Can the NHLBI and FDA’s CDRH, working together as sister agencies, develop strategies such as funding opportunities or collaborative... more »

Voting

4 net votes
19 up votes
15 down votes
Active
(@nhlbiforumadministrator1)

Goal 3: Advance Translational Research

Integrated Clinical Guideline on Comorbidities in Primary Care

The development of systematic evidence reviews (SER) that provide the evidence that partner organizations can use to develop an integrated clinical practice guideline for use by primary care providers for the treatment of patients with single and multiple conditions for the primary and secondary prevention of heart, lung, blood, and sleep (heart, lung, blood, sleep) diseases.

Voting

1 net vote
12 up votes
11 down votes
Active