Goal 2: Reduce Human Disease

To extend our knowledge of the pathobiology of heart, lung, blood, and sleep disorders and enable clinical investigations that advance the prediction, prevention, preemption, treatment, and cures of human disease.

Goal 2: Reduce Human Disease

Submitted by (@meier016)

Preventing hospitalization of asthma patients through agressive acute asthma management

Develop simplified agressive acute asthma treatment protocol and promote the implementation for primary care, ED, Urgent care, Internists, Pediatricians, Allergists, Pulmonologists, and Families. Goal is to prevent hospitalization of children and adults with asthma. For example: 3 cycles of Duoneb and Albuterol, monitoring pulsoximetry, with oral / IM Dexamethasone dosage. Also initiation of controller medication at ...more »

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Goal 2: Reduce Human Disease

Submitted by (@nhlbiforumadministrator)

Nontuberculous mycobacterial (NTM) lung infections

The true prevalence of Nontuberculous mycobacterial (NTM) lung infections remains incompletely understood, however several aspects of NTM lung disease prevalence are becoming more clear. NTM lung disease is currently more common in the U.S. than TB (by a factor of 3) and has consistently been shown to be increasing in prevalence. When viewed in the context of likely universal environmental NTM exposure this increasing ...more »

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Goal 2: Reduce Human Disease

Submitted by (@rhansler)

Conduct a clinical trial whether maximizing melatonin using orange eyeglasses in the evning reduces breast cancer.

Epidemiological studies have shown totally blind women have about half the incidence of breast cancer as blind women who retain light control of melatonin suppression or of women with normal vision. Studies show shift worker that reduces melatonin and disrupts the circadian rhythm increases the risk of breast cancer. Studies show human breast cancer grafts grown on rats but supplied with human blood grow rapidly if the ...more »

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