Goal 4: Develop Workforce and Resources

To support the future of investigator-initiated research by sustaining and developing a diverse biomedical workforce with the skills and research resources to pursue emerging opportunities in science.

Strategic Goal: Goal 4: Develop Workforce and Resources

Expanding short term Junior Faculty Training Programs such as the Summer Training Programs for Junior Faculty (PRIDE): Focus

Expanding the base of the program foci (e.g. including NCI in addition to the current HLBS).

Submitted by (@treva0)

Is this idea a Compelling Question (CQ) or Critical Challenge (CC)? : Critical Challenge (CC)

Details on the impact of addressing this CQ or CC :

Expanding the PRIDE program foci beyond NHLBI’s heart, lung, blood, and sleep foci, may involve a common-fund effort, for example by having multiple institutes involved in the program. It is well accepted that good research today is a collaborative effort that often reaches across institutes. For example, the research interests of several PRIDE/SIPID trainees were at the intersection of cardiology and areas such as cancer, diabetes and aging.

Name of idea submitter and other team members who worked on this idea : Treva Rice for the PRIDE (Programs to increase diversity among individuals engaged in health-related research): Joe GN “Skip” Garcia, Francisco Moreno Girardin Jean-Louis, Gbenga Ogedegbe, DC Rao, Victor Davila-Roman, Mohamed Boutjdir, Betty Pace, Juan Gonzales, Bettina M Beech, Keith Norris, Marino Bruce, Alicia Fernandez, Kirsten Bibbins-Domingo, and Margaret Handley.

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Strategic Goal: Goal 4: Develop Workforce and Resources

NOVEL APPROACHES TO TRAINING IN SLEEP AND CIRCADIAN RESEARCH

Sleep and circadian disorders are relatively new areas of medicine. Most universities currently lack a critical mass of investigators to develop institutional T32 grants. Thus, there are, unfortunately, few such programs nationally. The Sleep Research Society has recognized this and is taking active steps to facilitate development of other T32 institutional training grants. This will not, however, help the majority ...more »

Submitted by (@jnoel0)

Is this idea a Compelling Question (CQ) or Critical Challenge (CC)? : Critical Challenge (CC)

Details on the impact of addressing this CQ or CC :

The current status of research training in sleep and circadian disorders suggest that new approaches are needed. The field has developed one multi-center training grant to bring training to different institutions. This is focused on genetic/genomic approaches. It is run by the University of Pennsylvania which has a well developed program in this area. The fellows in training are, however, at other institutions, i.e., Johns Hopkins, University of Michigan and Stanford. Web-based approaches are used for work-in-progress seminars, grant development workshops and group mentorship, and didactic lectures. This strategy could be used more broadly to develop research training in other areas of sleep and circadian research. Stimulating this would have a major impact on research training in this new field of medicine.

 

Another relevant strategy would be to encourage adding slots in a competitive way for sleep/circadian research to other existing institutional T32 grants.

 

There are multiple mechanisms in place to communicate opportunities to the sleep/circadian academic community, i.e., Sleep-L, administered by the National Center for Sleep Disorders Research; Sleep Research Society biweekly blog; the Sleep Research Network. Specific encouragement of this approach would broaden the base for research training and would be of high impact.

Feasibility and challenges of addressing this CQ or CC :

The field of sleep and circadian research has had a long commitment to facilitating research training. The Sleep Research Society has hosted Trainee Day at our annual meeting for 20 years. The Sleep Research Society is funding early-stage investigators through its Foundation. The American Academy of Sleep Medicine runs, in collaboration with the NHLBI, an event at NIH for early-stage investigators in clinical research. The American Academy of Sleep Medicine Foundation has a “Bridge to K Award” program that provides funds to early-stage investigators who just missed funding on their first application for a K award. The Sleep Research Society has provided travel funds for early-stage investigators to attend recent workshops held by different NIH Institutes including National Heart, Lung and Blood Institute. Thus, there is no doubt of the commitment of the field and its professional organizations.

 

The impact of these new initiatives would be to broaden the base for research training beyond a few institutions. The number of institutions with a critical mass of investigators to mount successful T32 institutional training grants is not sufficient to provide the necessary future biomedical research workforce in this area. Novel approaches, based on modern communication IT technology, are needed.

Name of idea submitter and other team members who worked on this idea : Sleep Research Society

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Strategic Goal: Goal 4: Develop Workforce and Resources

Increase and Support Research Based Faculty

As the current chair of the Research and Training Division, I would like to convey that the AAAAI membership would like the NHLBI to consider the following in the development of its strategic plan: There has been a decline in research-based faculty in the past few years.  The challenge is two-fold.  First, increase the research faculty pipeline with increased focus on training and recruitment of research focused fellows ...more »

Submitted by (@wheeze)

Is this idea a Compelling Question (CQ) or Critical Challenge (CC)? : Critical Challenge (CC)

Name of idea submitter and other team members who worked on this idea : Mitchell Grayson on behalf of the American Academy of Allergy, Asthma, and Immunology

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Strategic Goal: Goal 4: Develop Workforce and Resources

Ask Dr. Hsia to stop littering the forum to advertise his company

True dialogue is impeded by having to constantly scroll through a repeated posting of the same company advertisement. This is abuse of the forum.

Submitted by (@savebasicresearch)

Is this idea a Compelling Question (CQ) or Critical Challenge (CC)? : Critical Challenge (CC)

Details on the impact of addressing this CQ or CC :

Comment by chsia 05/05/2015

Dear All,

1) Nano Red Blood Cell (NanoRBC) can be used alone or used conjunction with banked blood to improve the potency and safety of transfusable red blood cells.

 

etc.

 

Sincerely,

 

Carleton Hsia, Ph.D.

Chairman&CEO

NanoBlood LLC

Feasibility and challenges of addressing this CQ or CC :

Press Release

FOR RELEASE: Thursday, April 28, 2015

Contact: Natalie Likness, Governor’s Office of Economic Development, 605.773.3301

NanoBlood LLC Relocating to South Dakota

 

SIOUX FALLS, S.D. – NanoBlood LLC, based in Irvine, Calif., announced today that it is relocating to the South Dakota Technology Business Center (SDTBC) in Sioux Falls, S.D., to continue the regulatory and commercial development of its nano red blood cell as a life-saving drug in critical care and transfusion medicine.

 

etc.

 

“I am very grateful and appreciative of Gov. Daugaard’s support of commercial development of nano red blood cell in South Dakota for domestic and global need in critical care and transfusion medicine,” said Carleton Hsia, chairman and CEO of NanoBlood.

Name of idea submitter and other team members who worked on this idea : none

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Strategic Goal: Goal 4: Develop Workforce and Resources

Medical student research training in LMIC settings

What are the strategies for heart, lung, blood, sleep workforce to gain first-hand international experience in clinical research/implementation research training in low- and middle-income country (LMIC) settings?

Submitted by (@nhlbiforumadministrator1)

Is this idea a Compelling Question (CQ) or Critical Challenge (CC)? : Compelling Question (CQ)

Details on the impact of addressing this CQ or CC :

• Among the students who earn medical degrees in the United States, very few of them have been sufficiently trained to address the health needs of the most vulnerable populations.

• An international exposure in an LMIC setting would have enormous impact on clinical practice and research

• Any medical student interested in broadening their training may have opportunities for clinical and non-clinical hands-on experience and in turn this would increase number of physicians and researchers in global health.

Feasibility and challenges of addressing this CQ or CC :

Feasibility: • The NHLBI has a wealth of experience in training and career development programs in general and has supported and worked with global centers of excellence in this area.

• This experience can be used to leverage international experience in clinical practice and research outcomes in LMIC settings.

 

Challenges: • NHLBI would have to develop additional training mechanism(s) to foster clinical practice and research in an LMIC area.

 

• Resources for this unique training may be a challenge.

 

• Helping patients from vulnerable populations would involve confronting cultural differences and language barriers.

Name of idea submitter and other team members who worked on this idea : NHLBI Staff

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Strategic Goal: Goal 4: Develop Workforce and Resources

Align PhD Content with Careers Available to Recent PhDs

There is a need to create better alignment between the content of biomedical PhD programs and the careers that actually are available to those who have earned PhDs. Though available data are surprisingly weak, all the evidence suggests that only a small fraction (perhaps 15%) of current biomedical PhDs and postdocs are likely to find stable careers in academic research. Larger proportions are more likely to be employed ...more »

Submitted by (@teitelbaum)

Is this idea a Compelling Question (CQ) or Critical Challenge (CC)? : Critical Challenge (CC)

Name of idea submitter and other team members who worked on this idea : Michael S. Teitelbaum

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Strategic Goal: Goal 4: Develop Workforce and Resources

Distribution of funding

As long as funding remains at grossly inadequate levels, to distribute the research money more fairly, limit the total dollar amount any PI can receive. It should be a reasonably large number in order to fund multiple good ideas that are peer-evaluated, but small enough to allow more PIs to get funding.

Submitted by (@edward.fisher)

Is this idea a Compelling Question (CQ) or Critical Challenge (CC)? : Critical Challenge (CC)

Details on the impact of addressing this CQ or CC :

More PIs will get funding and the most talented investigators will still get support for multiple projects.

Feasibility and challenges of addressing this CQ or CC :

The old argument against this sort of thing is that the best ideas merit funding, but we already have % effort limits and if one carefully evaluates the multiple awards the most successful PIs get, there is usually some overlap. Also, the NIH in past surveys have found that bigger labs are less productive on a per person basis.So, even if there is no support for a firm number (like $1 million/year), better enforcement of % effort and overlaps should be done.

Name of idea submitter and other team members who worked on this idea : Edward A. Fisher

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Strategic Goal: Goal 4: Develop Workforce and Resources

Improving Biomedical Careers

There is a critical challenge to retain highly trained basic and clinical scientists in the biomedical research enterprise and expediently promote their independence and capacity to produce innovative discoveries. There is a need to provide more funding opportunities for collaborative, team-science approaches to scientific investigation by interdisciplinary teams comprised of clinician scientists, basic researchers, and ...more »

Submitted by (@nhlbiforumadministrator)

Is this idea a Compelling Question (CQ) or Critical Challenge (CC)? : Critical Challenge (CC)

Name of idea submitter and other team members who worked on this idea : NHLBI Staff

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Strategic Goal: Goal 4: Develop Workforce and Resources

Tobacco treatment education for medical students, residents, and fellows

There should be research on how best to educate medical students, residents, and fellows on strategies for effectively helping patients quit using tobacco products.

Submitted by (@szlewishcr)

Is this idea a Compelling Question (CQ) or Critical Challenge (CC)? : Critical Challenge (CC)

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Strategic Goal: Goal 4: Develop Workforce and Resources

Pharmacy-Physician Cross-Reference System Required

Why does a cross-reference gap occur when prescriptions are filled through a patient's one and only pharmacy. How can a pharmacist double check a physician's work when the physician prescribes a medication that should NOT be taken if the patient has a diagnosis the pharmacist has no documented evidence to REJECT the prescription and NOT dispense the dangerous drug-interaction, drug vs. medical condition information? Since ...more »

Submitted by (@louisecompanion)

Is this idea a Compelling Question (CQ) or Critical Challenge (CC)? : Critical Challenge (CC)

Details on the impact of addressing this CQ or CC :

#1) Tramadol/Ultram was prescribed by hospital discharging physician #1. Prescription paperwork clearly stated that Tramadol should not be administered if you take Cymbalta/Duloxetine. I took Tramadol and Cymbalta together for two (2) years.

 

#2) Seroquel/Quentiamine (generic name ??) was prescribed by physican #2. Prescription paperwork indicates this drug should NOT be taken with the drug SOTALOL/BETAPACE or patients who have Prolonged Q-T Interval or Long QT. I have Long QT and the pharmacist's response to filling the Seroquel prescription, which made me ill, was the Seroquel dose was not too high. That pharmacy also fills my Sotalol.

 

#3) I have been allergic to sulfa drugs. Physician #3 prescribed Polymyxin B Sulfate and Trimethoprim Ophthalmic Solution USP. I was initially prescribed the eye drops on 04-02-2015. Because my left eye continued to bother me, I returned to the same urgent care. I have a Medtronic ICD (implantable cardioverter defibrillator). Medical records clearly indicate that Sulfa drugs affect my cardiovascular system. On 04-14-2015, I returned to the same urgent care for eye pain but, based on my abnormal ECG, cardiovascular was my primary reason for the visit, not my eye. I was told to resume the Polymyxin (full eye drop name above).

 

I didn't find out this data until just recently. If the pharmacist KNEW I had Long QT, perhaps Seroquel would have NEVER been filled, which harmed my conditions.

Feasibility and challenges of addressing this CQ or CC :

Based on the above information, how can pharmacist's double check the doctor's (unfilled) prescriptions without knowledge of the patient's health history? How could a pharmacist fill a drug Seroquel when it shouldn't be combined with Sotalol or those with Long QT? How can this drug-interaction be avoided? How do we fill the gap? I am a serious disabled person who has exhausted herself because she HAS HAD to become a self-appointed, her OWN HEALTH ADVOCATE.

Name of idea submitter and other team members who worked on this idea : Louise Companion

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Strategic Goal: Goal 4: Develop Workforce and Resources

Pipeline of clinician scientists

Maintaining the pipeline of clinician scientists via early and mid-career awards. Promote the development of collaborative teams.

Submitted by (@societyforvascularsurgery)

Is this idea a Compelling Question (CQ) or Critical Challenge (CC)? : Critical Challenge (CC)

Name of idea submitter and other team members who worked on this idea : Society for Vascular Surgery

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Strategic Goal: Goal 4: Develop Workforce and Resources

Training Support for Non-Research-Intensive Institutions

Institutions that are less research intensive, which may characterize some of the Historically Black Colleges and Universities, Hispanic Serving Institutions and tribal institutions with primarily minority faculty and/or student body, may need additional support for training researchers and for performing both hypothesis driven and student integrated research to provide an environment conducive with NIH efforts to enhance ...more »

Submitted by (@treva0)

Is this idea a Compelling Question (CQ) or Critical Challenge (CC)? : Critical Challenge (CC)

Details on the impact of addressing this CQ or CC :

The grant submission process involves increasingly sophisticated administrative mechanics that many of these institutions do not have the resources to systematically or efficiently support with the requisite grant submissions and administration staff. For example, many challenges exist in putting together complex budgets with subcontracts, completing some (all) of the forms for on-line submission with increasing numbers of new RFA specific required documents, and recognizing the amount of time required to complete the submission process given the increasing number of previously not required mandates. In non-research-intensive institutions, there may be limited or no administrative support for these purely mechanical procedures, and additional training and resources are needed to support the increasingly complex grant process.

Name of idea submitter and other team members who worked on this idea : Treva Rice for the PRIDE (Programs to increase diversity among individuals engaged in health-related research): Joe GN “Skip” Garcia, Francisco Moreno Girardin Jean-Louis, Gbenga Ogedegbe, DC Rao, Victor Davila-Roman, Mohamed Boutjdir, Betty Pace, Juan Gonzales, Bettina M Beech, Keith Norris, Marino Bruce, Alicia Fernandez, Kirsten Bibbins-Domingo, and Margaret Handley.

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