Goal 4: Develop Workforce and Resources

To support the future of investigator-initiated research by sustaining and developing a diverse biomedical workforce with the skills and research resources to pursue emerging opportunities in science.

Goal 4: Develop Workforce and Resources

Increase participation in HLBS scientific disciplines

What strategies should NHLBI use to pursue students at the K-12 level of their education and also to encourage their scientific interests through the undergraduate and graduate levels?

Submitted by (@nhlbiforumadministrator)

Is this idea a Compelling Question (CQ) or Critical Challenge (CC)? : Compelling Question (CQ)

Details on the impact of addressing this CQ or CC :

An inspired healthcare related workforce will bring novel ideas and innovations to heart, lung, blood, and sleep (HLBS) related fields of science.

Feasibility and challenges of addressing this CQ or CC :

It is definitely feasible to develop or modify programs that will incentivize both students and teachers

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-9 net votes
8 up votes
17 down votes
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Goal 4: Develop Workforce and Resources

Creating research infrastructure through supporting the development of biorepositories and registries for rare lung diseases

Progress in rare lung diseases, such as interstitial lung diseases, has been hampered by a lack of patient-derived samples in large enough quantities or high-enough quality for systematic study. This is due to the inability of individual centers to recruit enough patients, and because of the varied samples each center obtains. Collecting, preparing, and storing such samples is not fundable by the NHLBI because it is not ...more »

Submitted by (@docew0)

Is this idea a Compelling Question (CQ) or Critical Challenge (CC)? : Critical Challenge (CC)

Details on the impact of addressing this CQ or CC :

The impact of addressing this Critical Challenge cannot be underestimated. Researchers throughout the country and the world are hamstrung by not being able to test hypotheses on reliable patient-derived samples. By supporting the creation of a biorepository of well-annotated, clinically-phenotyped biological samples from patients with interstitial lung disease, the scientific community will be able to attack many hypotheses simultaneously rather than individually as is currently the case. Utilizing an 'honest broker'-type system, researchers whose ideas have scientific merit will be able to access this trove of samples and data to confirm (or refute) their hypotheses. This type of resource does not exist but is critically needed.

Feasibility and challenges of addressing this CQ or CC :

Currently, few institutions care for a large proportion of interstitial lung disease patients nationwide. These institutions have already shown an ability to work together in other NHLBI-sponsored projects, such as IPFnet and LTRC. Thus, this project is feasible. Challenges that will need to be overcome include determining the appropriate samples to be collected, the centers that will participate in collecting samples and data, and identifying individuals or programs that can serve as an 'honest-broker' for this type of platform. However, engaging research partners among various centers has already been documented, with industry, academia, and patient advocacy groups coming together to support such an initiative.

Name of idea submitter and other team members who worked on this idea : Eric White

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-1 net votes
11 up votes
12 down votes
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Goal 4: Develop Workforce and Resources

Distribution of funding

As long as funding remains at grossly inadequate levels, to distribute the research money more fairly, limit the total dollar amount any PI can receive. It should be a reasonably large number in order to fund multiple good ideas that are peer-evaluated, but small enough to allow more PIs to get funding.

Submitted by (@edward.fisher)

Is this idea a Compelling Question (CQ) or Critical Challenge (CC)? : Critical Challenge (CC)

Details on the impact of addressing this CQ or CC :

More PIs will get funding and the most talented investigators will still get support for multiple projects.

Feasibility and challenges of addressing this CQ or CC :

The old argument against this sort of thing is that the best ideas merit funding, but we already have % effort limits and if one carefully evaluates the multiple awards the most successful PIs get, there is usually some overlap. Also, the NIH in past surveys have found that bigger labs are less productive on a per person basis.So, even if there is no support for a firm number (like $1 million/year), better enforcement of % effort and overlaps should be done.

Name of idea submitter and other team members who worked on this idea : Edward A. Fisher

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46 net votes
54 up votes
8 down votes
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Goal 4: Develop Workforce and Resources

Developing/adapting training programs to address future areas of critical need

What are the best methods to identify future training areas and develop/adapt training and mentorship programs to address future critical needs?

Submitted by (@nhlbiforumadministrator)

Is this idea a Compelling Question (CQ) or Critical Challenge (CC)? : Compelling Question (CQ)

Details on the impact of addressing this CQ or CC :

• Increased return on investment

• Cross-fertilization/cross pollinate with other ICs

Feasibility and challenges of addressing this CQ or CC :

High feasibility but may require pilot projects, marketing and dissemination

Name of idea submitter and other team members who worked on this idea : NHLBI Staff

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8 net votes
16 up votes
8 down votes
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Goal 4: Develop Workforce and Resources

Sickle cell education for healthcare providers

Although sickle cell was first described more than 100 years ago and more than 100,000 individuals in the US are living with sickle cell disease, healthcare providers still lack basic knowledge of the key components in providing care for individuals with sickle cell. This often leads to poor health outcomes including stigmatization of patients with sickle cell seeking care. Evidenced-based curriculum should be available ...more »

Submitted by (@coretta.jenerette)

Is this idea a Compelling Question (CQ) or Critical Challenge (CC)? : Critical Challenge (CC)

Name of idea submitter and other team members who worked on this idea : International Association of Sickle Cell Nurses and Physician Assistants, Inc.

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18 net votes
21 up votes
3 down votes
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Goal 4: Develop Workforce and Resources

Funding high risk/high reward ideas

There is a need to develop funding mechanisms for high risk/high reward ideas which have a high potential to open new paths for investigation in important fields which would lead to new discoveries.

Submitted by (@vfenik)

Is this idea a Compelling Question (CQ) or Critical Challenge (CC)? : Critical Challenge (CC)

Details on the impact of addressing this CQ or CC :

The new funding mechanisms would attract more ideas to the field.

Feasibility and challenges of addressing this CQ or CC :

A special expert teams would need to be created to review such applications.

Name of idea submitter and other team members who worked on this idea : Victor Fenik

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74 net votes
95 up votes
21 down votes
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Goal 4: Develop Workforce and Resources

Preserving and promoting expertise in integrative physiology

From my perspective, one of the key “critical challenges” facing the NHLBI in particular, and medical science in general, is to avoid being blinded by the promises of the reductionists in the “personalized, precision medicine” of the future. In order to understand the advances being made at the molecular level, we need to preserve and promote expertise in truly integrative physiology, what I like to call “PHYSIOMICS”. ...more »

Submitted by (@nhlbiforumadministrator)

Is this idea a Compelling Question (CQ) or Critical Challenge (CC)? : Critical Challenge (CC)

Details on the impact of addressing this CQ or CC :

Unfortunately, human physiologists are being squeezed out of the medical industrial complex by the basic scientists on one end, and the epidemiologists on the other. Most departments of medicine now require on 80/20 commitment to have a significant research component of an academic career, and it is becoming increasingly difficult for those few of us physiologists remaining to compete with the pressures of both research funding and clinical mandates. I urge the leadership at NHLBI to preserve a strong focus on human physiology, and continue to support the small, but high resolution studies that are required to answer key research questions. I would submit that studying an individual patient’s unique physiology is as much “personalized” or “precision” medicine as it is to read their genome. Remember, despite billions of dollars of research support, there remains nothing better to predict the risk of diabetes, than a simple measure of waist size!

Name of idea submitter and other team members who worked on this idea : Benjamin Levine

Voting

6 net votes
16 up votes
10 down votes
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Goal 4: Develop Workforce and Resources

What Training Outcomes are Significant?

What trainee outcomes will best fulfill the mission of NHLBI, and what programs best promote these outcomes?

Submitted by (@nhlbiforumadministrator)

Is this idea a Compelling Question (CQ) or Critical Challenge (CC)? : Compelling Question (CQ)

Details on the impact of addressing this CQ or CC :

A significant number of trainees do not become independent researchers but enter other career paths whose impact on the mission of NHLBI is unclear. A better understanding of the importance of these outcomes and the role of NHLBI-supported training in relation to our mission will inform the implementation and design of training strategies in the future.

Feasibility and challenges of addressing this CQ or CC :

OER is rapidly implementing automated approaches to replace the manual tracking of trainees and their subsequent career paths. This effort should facilitate our ability to look specifically at NHLBI-supported programs.

 

 

Challenge: Obtaining and integrating outcome data that is not included in NIH databases or eRA Commons

Name of idea submitter and other team members who worked on this idea : NHLBI Staff

Voting

-6 net votes
10 up votes
16 down votes
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Goal 4: Develop Workforce and Resources

Reducing Personal Education Debt

Because education debt weighs heavily on many early-stage physician-scientists, there is a need for the NHLBI to alleviate this problem and help boost the desirability of research career choices by automatically granting Loan Repayment Program awards to qualified investigators whose research projects are funded by peer-reviewed grants.

Submitted by (@nhlbiforumadministrator1)

Is this idea a Compelling Question (CQ) or Critical Challenge (CC)? : Critical Challenge (CC)

Name of idea submitter and other team members who worked on this idea : NHLBI Staff

Voting

-22 net votes
9 up votes
31 down votes
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Goal 4: Develop Workforce and Resources

Safeguarding Mentorship for the Next Generation

There is a need to ensure that mentors have adequate skills, time, and incentives to mentor successfully.

Submitted by (@nhlbiforumadministrator)

Is this idea a Compelling Question (CQ) or Critical Challenge (CC)? : Critical Challenge (CC)

Details on the impact of addressing this CQ or CC :

Continuity of research discoveries requires that outstanding mentors impart their passion and research skills to the next generation. Opportunities and incentives must be provided to ensure that highly qualified scientists can devote adequate time and effort to mentor promising junior colleagues, as well as enhance their own research output.

Feasibility and challenges of addressing this CQ or CC :

Mentor-directed opportunities can be immediately made available to provide protected time and salary for scientists with a passion for mentoring.

The current K24 mechanisms have been shown to be quite beneficial, not only for the mentor who can advance his career in the academe, but more so for the trainees who are exposed to the science that the mentor brings. However, K24 awards are primarily for patient-oriented research which enhance clinical skills. Non-clinical biomedical research will also benefit from similar programs.

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138 net votes
168 up votes
30 down votes
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Goal 4: Develop Workforce and Resources

Suipport new research using the R21 mechanism

The decision by NHLBI to not support the R21 mechanism may be stifling new and innovative research, partcularly by young investigators who do not have a track record of R01 funding. The critical challenge is to keep funding new ideas from younger investigators to keep their careers viable while they obtain the data and publications necessary for further R01-level funding.

Submitted by (@georgeporter)

Is this idea a Compelling Question (CQ) or Critical Challenge (CC)? : Critical Challenge (CC)

Details on the impact of addressing this CQ or CC :

The state of NHLBI funding rates for R01s are so low that we are undoubtedly loosing many young researchers as the fail to obtain adequate support for their research. Funding R21 grants will allow new, innovative, and perhps risky projects to proceed, while keeping less established researchers in the field. Re-establishing R21 funding may prevent the impression that NHLBI is more interested in supporting established labs and not advocating for and supporting new investigators.

Feasibility and challenges of addressing this CQ or CC :

Given the limited budget of R21s, they will not have as large an impact on the overall budget of NHLBI as the equivalent number of funded R01 grants. Therefore, this change is feasible from a financial standpoint. Obviously, funding R21s will decrease funding for other mechanisms. Finally, it is possible that many of these grants will not lead to advances in the field, but it is my understanding that studies show the same thing about R01s.

Name of idea submitter and other team members who worked on this idea : George Porter

Voting

87 net votes
101 up votes
14 down votes
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Goal 4: Develop Workforce and Resources

Expanding short term Junior Faculty Training Programs such as the Summer Training Programs for Junior Faculty (PRIDE): More Pgms

Expanding the training efforts (e.g. greater number of funded summer programs, extend training beyond 2 summers, provision for 5-year grants so an additional cohort can be included) would be highly beneficial.

Submitted by (@treva0)

Is this idea a Compelling Question (CQ) or Critical Challenge (CC)? : Critical Challenge (CC)

Details on the impact of addressing this CQ or CC :

Expand training efforts by increasing number of programs. The PRIDE is now turning away outstanding applicants due to the limited number of training slots across the different program. Since each program is currently training as many scholars as is feasible given their current infrastructure and resources, a solution may include increasing the number of independent programs in the PRIDE or number of trainees a given program can support. This will lead to increasing the number of independent researchers in the health-related fields who come from diverse backgrounds. Flexibility to increase the training period: Some junior faculty need more assistance than others. Some trainees from less research-intensive institutions may have had fewer opportunities to participate in research and thus have less experience and fewer (sometimes no) publications. They would greatly benefit from an initial period dedicated to increasing core research skills and publications prior to proposing and seeking independent grant funds. In the long run, they will be more likely to succeed given the extended training since the PRIDE offers opportunities to collaborate with nationally known researchers and provides access to data resources and the possibility of increasing their publication record. Also, a small percentage of the slots may be reserved for repeat participation in structured manner that provides escalating levels of support.

Name of idea submitter and other team members who worked on this idea : Treva Rice for the PRIDE (Programs to increase diversity among individuals engaged in health-related research): Joe GN “Skip” Garcia, Francisco Moreno Girardin Jean-Louis, Gbenga Ogedegbe, DC Rao, Victor Davila-Roman, Mohamed Boutjdir, Betty Pace, Juan Gonzales, Bettina M Beech, Keith Norris, Marino Bruce, Alicia Fernandez, Kirsten Bibbins-Domingo, and Margaret Handley.

Voting

5 net votes
11 up votes
6 down votes
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