Goal 1: Promote Human Health

To expand knowledge of the molecular and physiological mechanisms governing the normal function of heart, lung, blood, and sleep systems as essential elements for sustaining human health.
(@lesliesmyth)

Goal 1: Promote Human Health

Missing upper teeth & sleep apnea treatment: Problems?

I am a 73 year old female with Hypersensitivity Pneumonitis, Complex Sleep Neap, using oxygen @ 4-5 L/min 24/7 who just had my upper teeth extracted. I notice this has a negative effect, or appears to, on the effectiveness of apnea treatment. I wake several times during the night with lips flapping! This did not happen before the extraction. Because there are still some lower teeth, I am unable to close my mouth ...more »

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-42 net votes
5 up votes
47 down votes
Active
(@elyse.o.kharbanda)

Goal 1: Promote Human Health

Hypertension in children and adolescents - diagnosis and long term outcomes in large populations

Can we improve the thresholds for defining hypertension in children and adolescents based on risks for future adverse cardiovascular sequelae? In addition, can we to better understand how early identification of hypertension impacts long term health outcomes?

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12 net votes
16 up votes
4 down votes
Active
(@gaynor)

Goal 1: Promote Human Health

Improving longterm outcomes after surgery for congenital heart disease

Survival has improved but neurobehavioral disabilty remains a common complication with adverse impacts on quality of life, educational and occupational attainments, and resource utilization. There is increasing evidence that brain development is abnormal, and leads to a rrisk of peri-operative brain injury. Studies are needed to; 1. Further define the prevalence and spectrum of neurobehavioral disability. 2, Understand ...more »

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18 net votes
23 up votes
5 down votes
Active
(@klk370)

Goal 1: Promote Human Health

Basic understanding on the mechanisms of overeating

We have an in depth understanding of the effects nutrients and diet have on the development of chronic disease, yet very little research funding has gone to understanding the basic mechanisms of eating behavior and how to successful change diet. There are currently no study sections at NIH that specialize in nutrition and/or human eating behavior, and therefore proposals in this subject area get farmed out to other study ...more »

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-3 net votes
17 up votes
20 down votes
Active
(@media0)

Goal 1: Promote Human Health

THE RELEVANCE OF PREVENTION TRIALS

Prevention trials, implemented to reduce or delay progression to overt disease in a population at risk to the disease, are an important approach to health promotion. Therapies shown to reduce disease severity in patients with a specific disease are obvious, but not the only, candidates for a prevention trial in populations at high risk for prevalent diseases (such as heart failure, diabetes, COPD, asthma in children). ...more »

Voting

7 net votes
10 up votes
3 down votes
Active
(@psaty0)

Goal 1: Promote Human Health

What administrative changes might facilitate team science? Update peer-review and budget mechanisms for team science.

NIH peer-review methods were developed at a time when biomedical science was generally conducted by individual investigators. Approaches to defining conflict of interest in peer review that worked well for individual investigators may not be fit for the review of large-scale collaborative projects. Similarly, the subcontract mechanisms are often slow and cumbersome at a time when projects need to be nimble and timely. ...more »

Voting

54 net votes
74 up votes
20 down votes
Active
(@vlady.rozenbaum)

Goal 1: Promote Human Health

Establishing A Mobil Health Apps Monitoring Program

The recent Manhattan Research survey noted the increasing proliferation of health monitoring apps, which are accessible on mobile devices. Some experts believe that there are more than 40,000 of them already available. They mostly deal with wellness and fitness. The quality is very uneven and there is uncertainty among physicians which ones should be recommended to their patients.

Voting

27 net votes
40 up votes
13 down votes
Active
(@dburand)

Goal 1: Promote Human Health

Using video to replace the boring highly ineffective drug monographs that accompany prescrptions

Estimates are that less than 2% of medication monographs are actually read by patients. Of those 2% only 35% fully comprehend the material. Why not use video and simpler methods to educate patients about their medicine. By coding QR tags to direct patients to education websites, we solve the drive through phenomena, the health literacy issue, and the language barrier.

Voting

-12 net votes
4 up votes
16 down votes
Active
(@churv0)

Goal 1: Promote Human Health

Simplify cancer survivor followup

Excellent work has been done by Childrens Oncology Group and Childhood Cancer survivor group and the late effects of cancer treatment ,especially in children but also young adults is an ongoing field of study. However protocols for follow up studies ,which should be done and how often and by whom are very complicated and hard to follow. My idea is to develop a simple, relatively inexpensive and user friendly,protocol ...more »

Voting

4 net votes
10 up votes
6 down votes
Active