Goal 1: Promote Human Health

To expand knowledge of the molecular and physiological mechanisms governing the normal function of heart, lung, blood, and sleep systems as essential elements for sustaining human health.
(@jalees)

Goal 1: Promote Human Health

Achieving Excellence in Health and Science Communication

At least two thirds of US adults use the internet to access health information. The accuracy and quality of health and science information found on news media websites, corporate websites of the healthcare industry, blogs of healthcare providers and social media networks varies widely. Nevertheless, this information can have a profound influence on the healthcare-related decision-making of patients. The anti-vaccination... more »

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5 net votes
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(@glancast)

Goal 1: Promote Human Health

Updating level C evidence in Clinical Guidelines

Clinical Guidelines depends on good science. Despite this, only 11% of guidelines that reported level of evidence in 2009, had level of evidence A while 48% had level C. Studies have shown that recommendations based on Level of Evidence C (or their equivalence) are significantly less reliable and may be downgraded, reversed or omitted when better evidence is available. I propose a comprehensive review of ACC/AHA... more »

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(@nhlbiforumadministrator)

Goal 1: Promote Human Health

Continuous blood pressure and outcomes monitoring

Currently technology exists for continuous, non-invasive, insertable (not breaking any skin), blood pressure monitoring. At the same time micro-vascular health and whole body inflammatory response can be monitored continuously. The challenge is for the integration of these technologies into a simple device so we can begin to produce long term data on genetic and environmental influences on outcomes.

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11 up votes
12 down votes
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(@nhlbiforumadministrator1)

Goal 1: Promote Human Health

Developing tools and resources for studying sex differences

There is a need to promote sex balance in research. We know that existing and emerging scientific evidence supports the notion that sex is a major determinant for the development and progression of cardiovascular disease. Thus, expansion of resources for relevant animal models of disease, and the creation of databases that collect sex as a biological variable are important for both pre-clinical and clinical studies.

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15 net votes
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(@nhlbiforumadministrator1)

Goal 1: Promote Human Health

Engineering Healthy Lungs

What tools and knowledge are required to engineer healthy lungs? Can we engineer lungs and/or successfully modify cadaveric donor lungs using our understanding of matrix biology and lung development to provide a durable effective organ replacement therapy for patients with advanced lung disease?

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2 net votes
8 up votes
6 down votes
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