Goal 1: Promote Human Health

To expand knowledge of the molecular and physiological mechanisms governing the normal function of heart, lung, blood, and sleep systems as essential elements for sustaining human health.

Goal 1: Promote Human Health

Submitted by (@nhlbiforumadministrator)

Continuous blood pressure and outcomes monitoring

Currently technology exists for continuous, non-invasive, insertable (not breaking any skin), blood pressure monitoring. At the same time micro-vascular health and whole body inflammatory response can be monitored continuously. The challenge is for the integration of these technologies into a simple device so we can begin to produce long term data on genetic and environmental influences on outcomes.

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Goal 1: Promote Human Health

Submitted by (@rogerjahnke)

Qigong and Tai Chi for Chronic Disease Prevention

Non-pharmacological interventions for pain and stress have gained tremendous momentum. Mind-Body Practice -- Qigong and Tai Chi -- are group based and inexpensive to implement. The evidence base suggests that these practices are safe and effective for a multitude of preventable chronic disorders.. THE QUESTION: Given safety and efficacy, should there be vigorous research on implementation of Qigong and Tai Chi and ...more »

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2 net votes
33 up votes
31 down votes
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Goal 1: Promote Human Health

Submitted by (@jmrommes)

What is the potential effect of the burden of COPD on the US workforce?

COPD currently affects approximately 25 million individuals in the US alone, many of whom are of working age, according to the most recent BFRSS data. Many of those people are encouraged by their doctors or families to apply for disability and receive it, even though there are still jobs they could do. This is going to have an impact on business and industry as these people who are at the peak of their careers leave. ...more »

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8 net votes
15 up votes
7 down votes
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Goal 1: Promote Human Health

Submitted by (@wheeze)

Environmental Exposures and Atopic Disease

As the current chair of the Research and Training Division, I would like to convey that the AAAAI membership would like the NHLBI to consider the following in the development of its strategic plan:

 

What are the molecular and cellular responses in the lung that occur after environmental stimuli (including allergens) that predict homeostatic resilience or transition to atopic diseases?

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-7 net votes
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Goal 1: Promote Human Health

Submitted by (@lwli00)

Combinatorial intervention of immune dynamics to combat cariovascular disease

Human health and disease are modulated by complex and inter-connected dynamic processes. With particular significance, a well-balanced immune environment may play a key role in maintaining health and preventing the pathogenesis of cardiovascular disease. Defining the dynamic programming and balance of immune environment will be the key for combinatorial therapies to reset homeostasis.

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8 net votes
10 up votes
2 down votes
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Goal 1: Promote Human Health

Submitted by (@nhlbiforumadministrator1)

Smart Biomaterials for Self-Adjusting Implants

There is a need to leverage ongoing research on active materials (e.g., self-regenerating body armor, insulin-releasing polymers that respond to glucose, etc.) to stimulate the invention of new materials and constructs that are electrically, chemically and mechanically active to enable self-adjusting bioengineered implants.

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-4 net votes
9 up votes
13 down votes
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Goal 1: Promote Human Health

Submitted by (@heartjpc)

New technologies for Personalized health monitoring: too much or not enough

The development of personalized medicine and the increasing amount of information extracted from individual and patients throughout their life is expected to growth significantly. Multiple types of physiological sensors are currently embedded in everyday-life objects and yet their clinical value and their potential to improve health care is not well defined. It seems fundamental that the NIH develops a core research group/ ...more »

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5 net votes
13 up votes
8 down votes
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Goal 1: Promote Human Health

Submitted by (@nhlbiforumadministrator)

Glycans are critical for mammalian biology at a fundamental level

There is a pervasive view of glycobiology as a niche field that does not warrant significant attention. This is borne out of a profound ignorance. It is not an exaggeration to state that carbohydrates are just as important as proteins, nucleic acids, and lipids. Dismissing the impact of glycans is like stating that proteins are not very important to biology, and their importance is seen in the lethality of many mutations ...more »

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