Goal 4: Develop Workforce and Resources

Institutional Support for K applicants as they transition to independence

What can research institutions do to entice and support potential and actual K award applicants to become independent scientists?

Submitted by (@nhlbiforumadministrator)

Is this idea a Compelling Question (CQ) or Critical Challenge (CC)? : Compelling Question (CQ)

Details on the impact of addressing this CQ or CC :

The period between the end of the K award and the first R01 is a critical one wherein many trainees, with no financial support from their institutions, opt out of a science career and pursue other viable sources of income, such as in the clinics, in teaching, or in the private sector. An investment from their institution, either by way of bridge awards, protected time, or salary commitment will enable retention of these highly- trained individuals and ensure a vibrant research workforce in the years to come.

Feasibility and challenges of addressing this CQ or CC :

This type of activity can be initiated immediately by the private institutions as a way of motivating physician- scientists and other scientists to remain in the academe, and eventually reap the rewards by way of research awards that bring prestige and indirect costs back to the institution.

In an analysis of 132 NHLBI Division of Lung Diseases K08 grantees between FY2005-2011, only 52% applied for subsequent NIH grants, whereas 48% did not even try, suggesting more incentives should be given for them to stay within the biomedical research workforce. However, among the Early Stage Investigators (ESIs) funded in 2013, 58% had previous training grants, suggesting training grants give Research Project Grant (RPG) applicants a definite edge.

Name of idea submitter and other team members who worked on this idea : NHLBI Staff

Voting

74 net votes
102 up votes
28 down votes
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Goal 2: Reduce Human Disease

Reducing Patient Delay Times with ACS especially STEMI

The major barrier to further reducing mortality from ACS in particular STEMI remains patient delay. Symptoms are either ignored or misinterpreted and this behavior has not changed despite community education efforts. The advance of social media as well as smartphones and other internet based tools suggests that there is a new opportunity to potentially help change human behavior.

Submitted by (@dayam0)

Is this idea a Compelling Question (CQ) or Critical Challenge (CC)? : Critical Challenge (CC)

Details on the impact of addressing this CQ or CC :

The current patient delay time from symptom onset to seeking medical care is 2 hours. If we could reduce this to 1 hour we could further reduce ACS especially STEMI related mortality

Feasibility and challenges of addressing this CQ or CC :

The use of social media and smartphones to actively change public behaviors when experiencing potential medical conditions should be possible. Companies like Google and Facebook that have an interest in health could be approach to partner in this effort

Name of idea submitter and other team members who worked on this idea : Mohamud Daya

Voting

0 net votes
2 up votes
2 down votes
Active

Goal 4: Develop Workforce and Resources

Training and mentor support in global health

Why can’t all training grants (T, K, etc) be opened out to all people working in US institutions, regardless of citizenship or green-card?

Why can’t we establish mechanisms for US junior investigators and mentors interested in global NHLBI areas?

Submitted by (@nhlbiforumadministrator)

Is this idea a Compelling Question (CQ) or Critical Challenge (CC)? : Compelling Question (CQ)

Details on the impact of addressing this CQ or CC :

Current policy does not allow non-citizens and green-card holders to apply for most K and T grants. However, given the changing nature of US workforce, this policy needs to change. Current mechanisms do not easily enable US investigators to get support for global work……training and/or research.

Feasibility and challenges of addressing this CQ or CC :

Why not?

Name of idea submitter and other team members who worked on this idea : K.M. Venkat Narayan

Voting

-13 net votes
4 up votes
17 down votes
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Goal 2: Reduce Human Disease

Adequately powered clinical trials

Pragmatic and adequately powered clinical trials are an ongoing challenge.

­Develop new tools to facilitate identification and recruitment of subjects, remote/wireless data collection, and functional measures.

Submitted by (@societyforvascularsurgery)

Is this idea a Compelling Question (CQ) or Critical Challenge (CC)? : Critical Challenge (CC)

Name of idea submitter and other team members who worked on this idea : Society for Vascular Surgery

Voting

4 net votes
5 up votes
1 down votes
Active

Goal 2: Reduce Human Disease

Reducing CV events in breast cancer survivors -knowledge gaps

Identifying breast cancer survivors at high risk for CV morbidity and mortality to allow targeting of management strategies to reduce CV events and thereby improve overall cancer-related survival.

Submitted by (@nhlbiforumadministrator)

Is this idea a Compelling Question (CQ) or Critical Challenge (CC)? : Critical Challenge (CC)

Details on the impact of addressing this CQ or CC :

Chemotherapy for breast cancer stages I-III is known to be associated with or induce cardiotoxicity. Over 35% of these women develop progressive fatigue and exercise intolerance, and heart failure limiting their daily activities and frequently interfering with their ability to return to work. CV disease are the leading cause of morbidity and mortality for those surviving beyond 5 to 8 years from their breast cancer diagnosis. The excess of CV morbidity and mortality in these patients threatens to offset reductions in cancer-related survival. Identifying breast cancer survivors at high risk for CV morbidity and mortality could allow targeting of cardiovascular disease reducing therapeutic interventions.

Feasibility and challenges of addressing this CQ or CC :

creating a multisite registry of women with Stage 1-3 breast cancer scheduled to receive chemotherapy and a control population women of similar demographic and CV risk profile without neoplasia, would allow to collect data at baseline and during/after cancer treatment related modern therapy, pre/post treatment functional status, including fatigue, behavioral and psychosocial risk factors and quality of life, and serum biomarkers indicative of myocardial injury, fibrosis, and heart failure.

Name of idea submitter and other team members who worked on this idea : NHLBI Staff

Voting

-1 net votes
5 up votes
6 down votes
Active

Goal 2: Reduce Human Disease

Use Buteyko breath retraining to help patients manage and monitor their lung condition.

Buteyko Breath Retraining has been verified by the AHQR, Thorax Journal and other organizations as a legitimate technique to improve the symptoms of asthma and related respiratory illness. This simple technique could be instituted for a low cost to improve the quality of life of patients, reduce medications necessary for good control and save taxpayers and insurance companies a great deal of money.

Submitted by (@breathinglady)

Is this idea a Compelling Question (CQ) or Critical Challenge (CC)? : Critical Challenge (CC)

Voting

-15 net votes
1 up votes
16 down votes
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Goal 1: Promote Human Health

Screening for asymptomatic vascular disease

Does screening for asymptomatic vascular disease increase awareness, promote compliance with lifestyle interventions, and improve overall health?

Submitted by (@societyforvascularsurgery)

Is this idea a Compelling Question (CQ) or Critical Challenge (CC)? : Compelling Question (CQ)

Name of idea submitter and other team members who worked on this idea : Society for Vascular Surgery

Voting

0 net votes
2 up votes
2 down votes
Active