Goal 4: Develop Workforce and Resources

Enhance funding for population and public health research

Many challenges posted here focus on increasing translation and development of interdisciplinary teams. Diverse backgrounds and epidemiological training makes population and public health scientists ideal candidates to connect teams in different areas of research around translation to human health. While funding exists specifically for career development of physician and pre-clinical scientists, none exists for epidemiologists. ...more »

Submitted by (@mmongrawchaffin)

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Goal 4: Develop Workforce and Resources

R01 funding

Unless we fix and increase the R01 funding rate, which most basic scientists depend upon, we will continue to lose outstanding scientists of all ages and not have the next generation of scientists or the numbers of currently outstanding scientists to answer any of these compelling questions and critical challenges. Related to this, much has been written about the significant failure rate of clinical trials in part due ...more »

Submitted by (@parise)

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Goal 4: Develop Workforce and Resources

Distribution of funding

As long as funding remains at grossly inadequate levels, to distribute the research money more fairly, limit the total dollar amount any PI can receive. It should be a reasonably large number in order to fund multiple good ideas that are peer-evaluated, but small enough to allow more PIs to get funding.

Submitted by (@edward.fisher)

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Goal 2: Reduce Human Disease

Maintaining R01 Funding

Independent R01 are the lifeblood for biomedical research in this country. Reducing funding through this mechanism threatens the long term security of the research community and will cause young talented scientists to choose other careers. When funding is limited NIH should employ any measures available to maintain R01 a reasonable level of funding. This could be done by reducing indirect costs, large institutional awards ...more »

Submitted by (@gregory.morley)

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89 net votes
108 up votes
19 down votes
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Goal 3: Advance Translational Research

New funding mechanism for major diseases

According to the National Bioeconomy Blueprint" published in 2012 by the White House Office of Science and Technology Policy, “Flexibility in the use of new and existing funding mechanisms in and across agencies will be vital to stimulating the discovery of new bioinventions with potential to grow the bioeconomy” (p. 24). It is known that the most effective research program in American history was the Manhattan Project. ...more »

Submitted by (@soldatovn.humgenex)

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26 up votes
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Goal 2: Reduce Human Disease

Lack of Collaboration Across NIH Institutes

There are many significant questions in CVD prevention that cross the disciplines represented by the different institutes. For example, the obesity epidemic, poor nutrition, and physical inactivity are relevant to CVD, neurological disease, diabetes, and cancer. Tobacco use is directly relevant to cancer and CVD. Social determinants and disparities affect multiple diseases and outcomes. Reducing obesity will require interventions ...more »

Submitted by (@stephen.fortmann)

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7 up votes
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Goal 1: Promote Human Health

Sustainable funding

Our biggest challenge is sustaining domestic interest in research and science. The uncertainty of government funding and the long investment required for research are not compatible. Everything hinges on a reasonable chance at having a future in a chose career. I suggest a minimum of 20% funding level to ensure fairness and diminish politics.

Submitted by (@dfulton)

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Goal 2: Reduce Human Disease

Funding Limitations Block Intervention Research

The cap on R01 research grants at $500,000 per year has not changed in over 20 years. In the current fiscal crisis for research it has become an immovable block to submitting intervention studies (randomized clinical trials on treatment). Routine advice from NIH staff is to not even try for a larger study. The cap applies to every year, so one can design a trial that costs less than $2.5 million but exceeds $500,000 in ...more »

Submitted by (@stephen.fortmann)

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Goal 4: Develop Workforce and Resources

RO1 funding rate

I would like to suggest the following changes in RO1 funding: (1) Reduce the amount but maintain the duration of each RO1 award to make academic research labs SMALLER but BETTER - This will force PIs pay closer attention to experimental design, to improve the efficiency and accuracy. It may entice more PIs to do more experiments themselves, the best way to reduce errors, maintain consistency and keep in touch with the ...more »

Submitted by (@gtseng)

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