Goal 1: Promote Human Health

Global cohorts to fill gaps in knowledge

Given the global burden of disease, what does NHLBI plan to do to establish a diverse global cohort to connect basic sciences to population health, in a way that differences in phenotypes around the world can be studied rapidly? For example, why not start by supporting a coalition of cohorts originally funded by the Global Heart Initiative?

Submitted by (@nhlbiforumadministrator)

Is this idea a Compelling Question (CQ) or Critical Challenge (CC)? : Critical Challenge (CC)

Details on the impact of addressing this CQ or CC :

A big challenge is for global proposals to get through regular RO1 mechanisms, as the study sections tend to be US-centric. Issuing special RFAs for US institutions to collaborate with global partners and setting special study sections will help.

Feasibility and challenges of addressing this CQ or CC :

This should be feasible

Name of idea submitter and other team members who worked on this idea : K.M. Venkat Narayan

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Goal 3: Advance Translational Research

Culturally Specific Preventative research

There are ample research evidence related factors contributing to obesity,type 2 diabetes, cardiovascular disease.The research grant money is diverted heavily on "novel" topic such as genes.The preventative efforts are the key to tackle the issues.Often times,researchers on cardiovascular prevention find it difficult to add novel ideas to convince the grant reviewers in their application.There are many communities here ...more »

Submitted by (@athomas4)

Is this idea a Compelling Question (CQ) or Critical Challenge (CC)? : Critical Challenge (CC)

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Goal 4: Develop Workforce and Resources

Encouraging good science by maintinaing continuity of review

Challenge is to have revised grants reviewed by the same reviewers, rather than delayed by new sets of reviewers. Also, having points such as changing model species addressable through Program Staff rather than prolonged re-review.

Submitted by (@rlevine)

Is this idea a Compelling Question (CQ) or Critical Challenge (CC)? : Critical Challenge (CC)

Details on the impact of addressing this CQ or CC :

Faster advancement of science

Feasibility and challenges of addressing this CQ or CC :

Not hard!

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Goal 4: Develop Workforce and Resources

Shall we increase the transparency of the grant review process to prevent potential biases?

Financial and intellectual conflict(s) of interest are common in academic medical sciences. Those conflicts could potentially bias decisions of study section members and change grant application outcomes. During the grant review process, financial and/or intellectual conflict(s) of interest disclosures of the study section members are not readily available to the grant applicants or the public. Should the NHBI increase ...more »

Submitted by (@escalante.patricio)

Is this idea a Compelling Question (CQ) or Critical Challenge (CC)? : Critical Challenge (CC)

Details on the impact of addressing this CQ or CC :

Increased transparency in the grant review process will provide a more plain level field for all applications, including new investigators with novel ideas.

Feasibility and challenges of addressing this CQ or CC :

Public disclosure of financial (more than intellectual) conflict(s) of interest are becoming the standard in medical societies and scientific publications.

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Goal 4: Develop Workforce and Resources

Funding & Review Mechanisms

Funding and review mechanisms are essential resources that can facilitate or hinder innovative research to meet the NHLBI goals. These resources must be refocused to result in identification and funding of the type of innovative research being sought by NHLBI. The opportunities for leveraging available NHLBI funds with other sources should be considered formally as a component of overall budget planning, not just on ...more »

Submitted by (@media0)

Is this idea a Compelling Question (CQ) or Critical Challenge (CC)? : Critical Challenge (CC)

Details on the impact of addressing this CQ or CC :

The impact should be more equitable access to funds, as perceived by potential recipients; provision of funds for high-priority topics; and revitalized, refocused review groups that are willing and able to consider recommending high risk, innovative approaches.

Feasibility and challenges of addressing this CQ or CC :

This is a very specific challenge that may require incremental implementation with some experimentation/pretesting and solicitation of ideas from a range of stakeholders identified during this goal-setting exercise. While the Institute may be able to make changes in how funding mechanisms are employed, making changes to review group membership may be more challenging, especially in the current context of recruiting members. Incentives for this service may also need to be reviewed, innovatively, under current budget constraints.

Name of idea submitter and other team members who worked on this idea : Sonja McKinlay. Team Members: Susan Assmann and Paul Stark

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8 up votes
4 down votes
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