Goal 3: Advance Translational Research

Natural Experiments and Obesity

How can approaches, such as natural experiments, be used to capture the evolution and impact of policies/environmental change that are related to obesity? There needs to be a mechanism that can quickly support the funding of natural experiment research. For instance, NIDDK and NICHD participate in a rapid response PAR that funds natural experiments in a timely manner. It only takes about 4 months from when the application ...more »

Submitted by (@nhlbiforumadministrator1)

Voting

32 net votes
62 up votes
30 down votes
Active

Goal 4: Develop Workforce and Resources

Promotion of interdisciplinary science to address therapeutic challenges in cardiac arrhythmias management

The main therapeutic challenges that remain to be addressed in the field of cardiac arrhythmias generally require the participation of scientific expertises as diverse as physiology, medicine, engineering, chemistry, nanotechnology, material science and others. Today, there is little incentive to assemble such cross-expertise teams. Novel funding mechanisms could reward the time and effort invested in forming cross-expertise ...more »

Submitted by (@jeromekalifa)

Voting

-10 net votes
7 up votes
17 down votes
Active

Goal 2: Reduce Human Disease

COPD health maintenance experiment

There needs to be a rehab type maintenance study for COPD patients to determine if such a program would slow progression, improve health and reduce exacerbations/hospitalizations going forward. Thus, reducing costs to patient/hospital/public aid programs.

Submitted by (@patgaramella)

Voting

9 net votes
16 up votes
7 down votes
Active

Goal 2: Reduce Human Disease

Consequences of drug interactions leading to QTc prolongation

Better understand the consequences of drug interactions leading to QTc prolongation. About 1/3 of cardiac ICU patients develop QT prolongation and about 45% receive drugs that are possibly contributing to this problem. The full spectrum of contributors and causes, as well as the patient-centered and health-system-centered clinical outcomes, are not known.

Submitted by (@greg.martin)

Voting

-1 net votes
1 up votes
2 down votes
Active