(@gaynor)

Goal 1: Promote Human Health

Improving longterm outcomes after surgery for congenital heart disease

Survival has improved but neurobehavioral disabilty remains a common complication with adverse impacts on quality of life, educational and occupational attainments, and resource utilization. There is increasing evidence that brain development is abnormal, and leads to a rrisk of peri-operative brain injury. Studies are needed to; 1. Further define the prevalence and spectrum of neurobehavioral disability. 2, Understand ...more »

Voting

18 net votes
23 up votes
5 down votes
Active
(@nhlbiforumadministrator)

Goal 2: Reduce Human Disease

Longitudinal Outcomes in Adults with Congenital Heart Disease

There is a critical need in congenital heart disease to assess longitudinal medical and psychosocial outcomes in older children and adults in the U.S. Current data in this area, particularly in the adult population, is limited to single center or small multicenter efforts or registry/population data from other countries. Understanding the long-term aspects of care is necessary not only to provide lifelong high quality ...more »

Voting

11 net votes
15 up votes
4 down votes
Active
(@nhlbiforumadministrator1)

Goal 3: Advance Translational Research

Obesity in special needs populations: Congenital heart disease

What are effective prevention and treatment strategies for populations with special needs, such as those with congenital heart disease, Down syndrome and preterm-born, to maintain a healthy weight?

Are there successful strategies derived from "normal" populations that could be effectively applied to these populations?

Voting

-24 net votes
12 up votes
36 down votes
Active
(@jamesr.priestmd)

Goal 2: Reduce Human Disease

Understanding the Genetic & Epigenetic Basis of Congenital Heart Disease?

Over the last thirty years, our fundamental understanding of the genetics and pathogenesis of congenital heart disease has lagged the tremendous advances in the surgical and clinical care of infants with this group of disorders. We need to close this gap with investigation into the genetic basis of congenital heart malformations to develop new models of disease. The goall is translate an improved molecular genetic and ...more »

Voting

22 net votes
37 up votes
15 down votes
Active
(@dstephens)

Goal 2: Reduce Human Disease

Promotion of human health and reduction of human disease

Congenital heart disease (CHD) is the most common birth defect and leading cause of defect-related infant mortality. With nearly 1 in 100 babies born annually with CHD, the needs of children and adults born with CHD are ongoing and costly. More focused research into CHD promotes human health and will result in a better quality of life, reduced premature death and lower healthcare costs.

Voting

0 net votes
1 up votes
1 down votes
Active
(@dstephens)

Goal 3: Advance Translational Research

Advancing Translational Research

Ensuring that basic science is translated into clinical practice is essential. While there have been great strides in ensuring that babies born with congenital heart defects (CHD) are identified and repaired, we know that there are lifelong implications for those with CHDs that require continued follow-up and treatment. As the proportion of those with CHDs as adults continues to outpace the pediatric population, we urge ...more »

Voting

2 net votes
4 up votes
2 down votes
Active