Goal 2: Reduce Human Disease

Submitted by (@tosinola)

Impact of each VOC Crisis in patients with sickle cell disease

While the long term cumulative effects of frequency, duration and severity of VOC on mortality is known in SCD, there is little known about the impact of each individual crisis or the amount of damage during crisis versus background smoldering ischemia from the disease. Any effort in quantifying this for SCD in the absence of interventional agents initially, and then as a potential measurement of the benefit of drug ...more »

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Goal 4: Develop Workforce and Resources

Submitted by (@sfisher1)

scientific community in crisis- plans for stabilization

From my discussions with scientists at other universities and my own experience the scientific community is now in crisis akin to the recent crises in the housing and finance sectors. If not stabilized the damage is likely to be severe and long-lasting. The NIH/NHLBI as the vehicle for investment of the public's money in this enterprise has a responsibility to take IMMEDIATE action. My suggestions include 1) limit salary ...more »

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