(@nhlbiforumadministrator1)

Goal 3: Advance Translational Research

The Investigator's Catch-22: How Can NHLBI Help?

The Critical Challenge is to determine how NHLBI can continue to foster the translational research necessary to allow our researchers to further develop their NHLBI-funded basic science discoveries. Researchers can't readily get a "typical" grant to perform the preclinical and early clinical translational IND-enabling research, and also can't yet attract private sector support without having done the work to "de-risk"... more »

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10 net votes
21 up votes
11 down votes
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(@nhlbiforumadministrator1)

Goal 3: Advance Translational Research

Expand the H3Africa Partnership Model to Decrease HLB diseases

Is there a way to decrease the risks for HLB disease leveraging the H3Africa genomics platform? • Leverage partnerships providing resources to the H3African populations • Identify the best collaborative partners to reach out to the low resource population • Find the best mechanism for collaborations to facilitate the interventions in low resource settings • Merge NHLBI research objectives and goals with those of potential... more »

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-6 net votes
6 up votes
12 down votes
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(@nhlbiforumadministrator)

Goal 3: Advance Translational Research

Implementation science research to reduce adverse effects of SCD

From various publications and reports, we have characterized the risks associated with sickle cell disease (SCD) and understand many of the barriers for treatment of SCD in LMICs. How can implementation science research be used to reduce the negative outcomes of SCD in low/middle income countries?

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18 net votes
31 up votes
13 down votes
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(@dbdb00)

Goal 3: Advance Translational Research

Develop common-sense standards for obesity research

Obesity research is riddled with methodological problems that are rarely challenged, leading to the perpetuation of misinformation and interventions that do harm. Given the two-thirds of the population who are classified as higher weight and thus subject to these interventions, it is past time to clean up the basic scientific flaws in this research area. For a quick summary of a couple of these issues, see Poodle Science:... more »

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24 net votes
44 up votes
20 down votes
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(@nhlbiforumadministrator)

Goal 3: Advance Translational Research

Culturally competent T4 research interventions to reduce heart, lung, blood, sleep

Using previous federal and partner infrastructure, what are the best methods to promote culturally competent T4 interventions that will reduce cardiopulmonary risk factors in global populations with a disproportionate burden of heart, lung, blood, sleep diseases?

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-7 net votes
9 up votes
16 down votes
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(@nhlbiforumadministrator)

Goal 1: Promote Human Health

Human normal variation and resilience across lifespan

What is the measureable normal human variation at the -omic, cellular, organ, and system levels within the population and across the lifespan? • What are the range of normal human cellular functions that create resilience at all levels—cells, organs, organ systems? • What inter-organ, tissue, and cellular communications maintain individual health and the health of populations? • How do we understand why individuals with... more »

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19 net votes
26 up votes
7 down votes
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(@dayam0)

Goal 4: Develop Workforce and Resources

Enhancement of the Medical Home and Medical Community with the use of EMS providers

Traditionally the Health Care model has meant that patients come to HCF for their care. Hospitals are increasingly overcrowded and also not always the best place to be due to the risk for nosocomial infections. Utilizing existing community resources to enhance the health both acute and chronic deserves exploration at the national level. Training paramedics to do chronic disease monitoring as well as as remotely work with... more »

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3 net votes
4 up votes
1 down votes
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(@nhlbiforumadministrator)

Goal 3: Advance Translational Research

Implementation of T4 Translation Research Platforms and Networks

How can cost-effective implementation of late stage translation (T4) research protocols be facilitated for heart, lung, blood, sleep diseases and health inequities?

Can research platforms and networks be created and utilized to facilitate execution of multi-level interventions and approaches for the end user in collaboration with key stake holders?

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4 net votes
13 up votes
9 down votes
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