Why is Early Stage Investigator defined as New Investigators who are within 10 years of completing their terminal research degree or within 10 years of completing their medical residency at the time they apply for R01 grants? This provides an unfair advantage to all PhD, general surgeons, internists, and pediatricians compared to subspecialists who complete clinical training 3-6 yrs after general training.
SBIR STTR programs currently offer funds to support phase 1 and phase 2 development of translation with corporate involvement. Several here have pointed out that there is need for additional NIH support of investigator initiated translation, and I concur. There is indeed need for early stage and pre-IND support. Such a program would support relatively small grants for proof-of-principle studies, pre-clinical work needed... more »