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Ideas Contributed [ 3 ] [+]
The prevalence of cardiometabolic disorders of pregnancy are increasing rapidly in women in the United States, particularly in black women. These disorders have a significant impact on the development of CVD in women as they age and on their offspring. The science to answer these questions are both mechanistic(understanding underlying mecanism of disease, esp preeclampsia) and behavioral. New methods of gathering ...more »
Precision medicine will be invested in across NIH, as per the President's "Precision Medicine Initiative". It is critical that the population base be reflective of the US population, including 50% women. Gender, especially as it relates to exposures, must be a dominant consideration, as these factors are critical to the development of human disease and therefore will be important to prevention.
There are compelling data regarding the sex-dependent intersection of depression and cardiovascular disease (both IHD and stroke). There are early data suggesting the underlying mechanisms. CVD is the number one cause of death in women and depression is the number one cause of disability with women 70% more likely to experience depression over their lives. The underlying sex-dependent mechanism is important to elucidate. ...more »