Thank you for participating!

Thank you to all who contributed to the National Heart, Lung, and Blood Institute (NHLBI) Strategic Visioning Forum. Ultimately, over 1,000 ideas were submitted, with more than 42,000 votes. This remarkable response exceeded expectations and provided a wealth of ideas to draw upon as NHLBI moves forward. Please visit the NHLBI Strategic Visioning page to find out more about the NHLBI Strategic Visioning process.


Welcome to the National Heart, Lung, and Blood Institute (NHLBI) Strategic Visioning Forum. The Institute is gathering ideas for the most compelling scientific priorities in the four NHLBI Strategic Goals to address over the next decade.

(@camarell) kudos icon +

Goal 2: Reduce Human Disease

Reduce the immunological burden of Heart Transplantation.

The research in the field of heart transplantation is importantly targeted to minimization of the undue toxicity of immunosuppressive regimens. This practice is limited by the natural tendency to develop chronic and humoral rejection if immunosuppression is too low.
Allocation of organs in Heart Transplantation (HTx) is traditionally limited by the logistic of donation (Cold Ischemic Time) and by the urgency of recipients.... more »

Voting

0 net votes
1 up votes
1 down votes
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(@nhlbiforumadministrator1) kudos icon +

Goal 3: Advance Translational Research

Integrated Clinical Guideline on Comorbidities in Primary Care

The development of systematic evidence reviews (SER) that provide the evidence that partner organizations can use to develop an integrated clinical practice guideline for use by primary care providers for the treatment of patients with single and multiple conditions for the primary and secondary prevention of heart, lung, blood, and sleep (heart, lung, blood, sleep) diseases.

Voting

1 net vote
12 up votes
11 down votes
Active
(@nhlbiforumadministrator) kudos icon +

Goal 4: Develop Workforce and Resources

Quantitative training in the era of big data

Should training in biostatistics, computer science, bioinformatics become broader for the entire biomedical community in this era of very large data sets?

 

How can we grow the number of specialists in biostatistics (and these related fields) without causing an oversupply?

Voting

40 net votes
55 up votes
15 down votes
Active
(@dcenter) kudos icon +

Goal 2: Reduce Human Disease

Improve Repair of injured lung

Why can’t we improve outcomes following acute lung injury. A half century of ICU interventions have resulted in only incremental improvements in survival and morbidity following acute lung injury. While we have pursued innumerable strategies for decreasing ventilator associated exacerbation of lung injury, we have failed to identify treatable common or selective pathways from the initial injury that can be targeted post... more »

Voting

5 net votes
8 up votes
3 down votes
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(@tosinola) kudos icon +

Goal 2: Reduce Human Disease

Impact of each VOC Crisis in patients with sickle cell disease

While the long term cumulative effects of frequency, duration and severity of VOC on mortality is known in SCD, there is little known about the impact of each individual crisis or the amount of damage during crisis versus background smoldering ischemia from the disease. Any effort in quantifying this for SCD in the absence of interventional agents initially, and then as a potential measurement of the benefit of drug... more »

Voting

3 net votes
3 up votes
0 down votes
Active
(@nhlbiforumadministrator) kudos icon +

Goal 3: Advance Translational Research

Implementation of checklist to improve outcomes of COPD patients with acute exacerbations

Implementation of checklist to improve outcomes of COPD patients with acute exacerbations

 

• Does implementation of a checklist designed to improve the care of patients with COPD exacerbations result in greater adherence to guideline recommendations?

 

• Does implementation of a checklist designed to improve the care of patients with  COPD exacerbations results in improved patient outcomes?

Voting

3 net votes
3 up votes
0 down votes
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(@grang001) kudos icon +

Goal 3: Advance Translational Research

Preventing Stroke from Atrial Fibrillation

How can health systems develop and implement validated measurement and feedback tools to identify patients with atrial fibrillation, categorize their risk factors for stroke, capture reasons for non-treatment, and develop interventions customized to those reasons to substantially improve the proportion of patients receiving effective oral anticoagulant stroke prevention treatment?

Voting

6 net votes
8 up votes
2 down votes
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(@marcozenati) kudos icon +

Goal 3: Advance Translational Research

Leverage Information Technology to Improve Patient Safety in Surgery

Progress toward a six-sigma level of safety (already achieved in commercial aviation) has been slow in medicine and surgery. The best cardiac surgery program operates at only 3.5 sigma level. In order to acceletate this process, it is critical to leveage recent advances in information technology, including but not limited to natural language processing (NLP), advanced speech recognition, artificial intelligence.

Voting

-8 net votes
3 up votes
11 down votes
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(@nhlbiforumadministrator1) kudos icon +

Goal 3: Advance Translational Research

Obesity in special needs populations: Congenital heart disease

What are effective prevention and treatment strategies for populations with special needs, such as those with congenital heart disease, Down syndrome and preterm-born, to maintain a healthy weight?

Are there successful strategies derived from "normal" populations that could be effectively applied to these populations?

Voting

-24 net votes
12 up votes
36 down votes
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(@efimov) kudos icon +

Goal 3: Advance Translational Research

NHLBI Cardiovascular Engineering Strategy

Most impressive and impactful advances in CV diagnostics and therapies came in the last 50 years from CV engineering, including implantable devices and imaging technology. CV engineers are developing next breakthrough technology including tissue engineering and flexible electronics. However, organizational structure of NIH does not have an entity responsible for strategic development of CV engineering. NIBIB does not... more »

Voting

8 net votes
17 up votes
9 down votes
Active
(@dgutt0) kudos icon +

Goal 4: Develop Workforce and Resources

Leveraging support from local institutions

Create a "Center of Excellence" designation in Cardiovascular Research akin to NCI's Comprehensive Cancer Center designation. Specific qualifications for such a designation will need to be defined. However this will encourage institutions to invest heavily in CV research to support such designation. In this way, local institutions will partner with NHLBI to support discovery in heart and vascular research.

Voting

-17 net votes
13 up votes
30 down votes
Active