The Challenge is to make behavioral weight loss programs readily available to he many overweight and obese patients who need them. Behaivoral weight loss programs are effective in producing weight losses of 7-10% of initial body weight, which has been shown to have major beneficial effects on a number of diseases relevant to NHLBI--including hypertension and sleep apnea. However, at present, these programs are not widely available. Efforts to scale these programs through Internet have been successful. Further research is needed to determine how to disseminate these programs more broadly--should it be through physicians? community partners? pharmacies?