Goal 3: Advance Translational Research

Implementation Research to Improve Global Availability of Safe Blood Transfusions

What well-developed principles and lessons learned can be employed to improve the safety and availability of blood transfusions in developing countries?


The WHO Global Status Report 2013, many research reports, and a recent assessment of burdens of transfusion transmissible infections with HIV, HBV and HCV identified several critical challenges: 1) Significant proportions of blood collections in a large number of countries are being conducted without oversight by national health authorities, for which little is known about their donor safety profile, donation screening practice and overall quality schemes; 2)Lack of adequate supply of blood for transfusion in many countries makes it difficult to eliminate paid blood donations even though it is well known that such donations are not safe; 3) One of the major reasons is the lack of voluntary non-remunerated blood donors and donations (VNRBD); 4) International efforts, including those by the US, have helped many countries establish quality blood supply systems to improve blood safety and availability but the challenge is to sustain such systems without continual external financial support, that is, the challenge is to establish and maintain quality blood supply systems cost-effectively to make them sustainable.

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Idea No. 95