Goal 3: Advance Translational Research

Understanding heterogeneity in ARDS

ARDS is a syndrome, yet we treat it as though it was a single clinical disease. There has been success in improving the process of care for patients with ARDS, but no real progress on address the underlying process. For successful therapies to influence the disease process, we need to be able to distinguish the mechanisms active in individual patients and so that we can design and test interventions targeting the specific pathophysiology in the individual. We have begun to address this kind of issue in COPD, but have made limited progress in ARDS.

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Idea No. 960