Goal 2: Reduce Human Disease

Understanding of chronobiological systems

We know that all life functions are based on circadian and other rhythms; chronobiological systems are interdependent in intricate ways. Disturbances and disorders in one part of a system may affect other vital systems in unexpected but far-reaching ways.


Many aspects of circadian rhythms and sleep-wake regulation in normal, healthy humans have been charted. Much of the knowledge thus gained is assumed to be valid also for people with intrinsic CSWDs. However, only research on actual patients will show whether this assumption is correct. As patients getting today’s state-of-the-art advice seldom get good results, they must continue to live with the symptoms and the stigma (lazy, inconsiderate, untrustworthy).

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Idea No. 1128