Showing 4 ideas for tag "assist"
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Goal 2: Reduce Human Disease

Optimal Use of mechanical circulatory support devices to Minimize Pump Thrombosis & AEs

There is a need for the development of a collaborative observational study that leverages off of existing registries, such as INTERMACS and STS, that will follow mechanical circulatory support devices (mechanical circulatory support device) patients prospectively and collect process-of-care data to identify 1) optimal approaches for the management of patients and 2) pumps to minimize the occurrence of adverse hemodynamic... more »

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15 up votes
11 down votes
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Goal 3: Advance Translational Research

Engineering Challenges for Next Generation VADs

Critical challenges to overcome include the development of non-platelet activating impellers and hypothrombogenic surfaces in modern ventricular assist devices (VADs). Percutaneous and transcutaneous electric drive systems will need to evolve, and clinical research is needed to reduce thromboembolism and bleeding (acquired von Willebrand syndrome). Adverse events may also be further reduced if smaller pumps, for partial... more »

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6 net votes
27 up votes
21 down votes
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Goal 3: Advance Translational Research

Risk Mitigation of Implantable Cardiovascular Devices

There is a serious need to improve implantable cardiovascular devices to eliminate, or at least substantially reduce, the risk of serious adverse events from occurring to more effectively treat patients.

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23 down votes
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Goal 2: Reduce Human Disease

Regeneration of Failing Heart while Resting on Left Ventricular Assist Device

Heart transplant is the ultimate treatment for AHA stage-D heart failure. Due to availability, heart transplants will be limited to about 2,500 per year. Patients with AHA stage-D heart failure has estimated prevalence of 0.2% for age >45. Thus, patients in need far exceed organs available. A failed heart has very challenging environment for cellular therapy. Left ventricular assist device (LVAD) can offload the heart... more »

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7 down votes
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