Host and environmental factors effect on transplantation biology and regenerative medicine
• How does inflammation and cell injury induce the immune system during transplant rejection?
• How do we control immune responses to enable cell and tissue regenerative strategies?
• How do we use iPS cell based and gene editing based therapies... more »
Voting
Human normal variation and resilience across lifespan
• What are the range of normal human cellular functions that create resilience at all levels—cells, organs, organ systems?
• What inter-organ, tissue, and cellular communications maintain individual health and the health of populations?
• How do we understand why individuals with... more »
Voting
Computational biology modeling approaches
There is a need to develop computational biology modeling approaches to study normal variation in heart, lung, blood, and sleep (HLBS) systems.
Voting
Goal 4: Develop Workforce and Resources
Establishment of an independent study section on Pulmonary Vascular Biology and Translational Research
Voting
A Systems Approach - Human Cardiac Electromechanical Activity
Voting
The effects of environmental factors on heart, lung, blood, sleep disease development across the lifespan
How do growth, development, exposure, and behavior affect heart, lung, blood, sleep disease development and outcome throughout the lifespan?
How do you improve organ function/capacity during childhood?
Voting
Systems approaches to understand the pathogenesis of cardiovascular diseases, combined with in vivo validation
Voting
Intersecting Developmental Biology with Vascular Physiology and Biology
Voting
Do our modern "traditional" sleep schedules defy nature?
http://www.bbc.com/news/magazine-16964783
So, maybe the majority of our modern societies (even the people without recognized sleep disorders) are unwisely fighting against biology?
Perhaps a lot of people's health issues, such as... more »
Voting
Goal 4: Develop Workforce and Resources
Training approaches in lymphatic biology
Voting
How to maximize the opportunities and promise of emerging omics research? Develop scientific commons
Voting
Goal 3: Advance Translational Research
Human Heart Systems Biology
Voting
Vascular biology and the pathophysiology of sepsis
Voting
National network to study the pathobiology of sepsis
Sepsis is the leading cause of death in hospitalized patients, the 3rd leading cause of death in all people in the US, the most common condition leading to widespread vascular collapse, among the most common causes of respiratory failure, and a frequent cause of acute cardiac dysfunction.