Can detailed longitudinal study of lung disease in infancy/early childhood improve our understanding of the origins of obstructive airways disease, and the variation seen in asthma phenotypes and severity?
What is the natural history of the best characterized ChILD disorders (surfactantrelated sequence variants, neuroendocrine cell hyperplasia of infancy (NEHI),pulmonary interstitial glycogenosis (PIG),idiopathic pulmonary hemosiderosis)?
What is the relationship of ChILD disorders to adult diffuse lung disease?
What is the relationship of ChILD disorders to more common childhood respiratory diseases?
What is the relationship of ChILD disorders to other clinical populations that manifest ILD?
How can we improve communication between schools and clinicians in order to develop support systems for children with severe asthma with health disparities?
How can we eliminate inefficiency in medical communication to better serve children with severe asthma?