Interaction of blood cells with their environment
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Predictive biomarkers
What biomarkers of acute environmental exposure are predictive of disease onset or progression?
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What is the role of the environment in HLB disease etiology
It is clear that genetic sequence variation does not account for a substantial portion of disease burden. It is likely that the broad environment contributes to HLB disease via epigenomic alterations and interaction with genetic variants. There is an urgent need to understand the environmental contribution to disease as most exposures are modifiable and are targets for prevention interventions.
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Enhancing Understanding of Determinants of Health in Rural Areas & Developing Solutions
What are the biological, environmental, social and economic determinants of health in rural areas related to COPD and other lung disease.
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Making It Real: Affordable Physiologically Relevant In Vitro Environments
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Lung cell stimuli responses
What alterations in respiratory epithelia in response to environmental / external insults are irreversible and lead to disease onset or progression?
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What are the Determinants of Short Term Prediction of Heart Attacks?
In spite of many years of research, we still cannot predict the short term risk of a heart attack or sudden CHD death. Most CHD deaths occur outside of the hospital. In spite of improvement of out-of-hospital emergency care, most “sudden death events” are still not successfully resuscitated.