Showing 5 ideas for tag "intervention"

Goal 2: Reduce Human Disease

Can Psychological Science Improve Weight Loss?

Will sensitivity to the psychological aspects of obesity, including lifestyle priorities and motivations, improve the efficacy of long-term effectiveness of weight loss and obesity prevention interventions?

Is this idea a Compelling Question (CQ) or Critical Challenge (CC)? Compelling Question (CQ)

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A primary focus on principles of psychology may result in significantly improved control of the obesity epidemic. Effective interventions could reduce the risk of diabetes, sleep apnea, and hypertension. This research could also affect clinical practice guidelines for weight loss and obesity treatment.

Feasibility and challenges of addressing this CQ or CC

Psychological science has been successful in developing effective treatments for a number of conditions, including sleep disorders, depressive symptoms, anxiety and phobias. Many of the behavioral principles employed in such interventions (e.g., cognitive restructuring, motivational methods) could be translated for the prevention and treatment of obesity within a reasonable time frame. Additional attention should be directed to the needs of population subgroups in which obesity is most prevalent.
In their Viewpoint article on weight loss intervention research, Pagoto and Appelhans (JAMA, 2013, see attachment) question whether a continued focus on dietary factors in research on weight loss and obesity is warranted. Their commentary raises the importance of attention to the individual psychological characteristics that influence adherence to weight loss interventions rather than dietary composition.

Name of idea submitter and other team members who worked on this idea NHLBI Staff

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Goal 3: Advance Translational Research

Building Effective Interventions for Heart-Healthy Eating

What translational science approaches are best able to test individual, community, and environmental approaches for increasing adherence to heart-healthy dietary recommendations, such as the Dietary Approaches to Stop Hypertension (DASH) diet?

What are the most effective types of interventions (e.g., personal coaching, print material, interactive internet content, faith-based community programs, campaigns) and tools... more »

Is this idea a Compelling Question (CQ) or Critical Challenge (CC)? Compelling Question (CQ)

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This information will inform intervention, education, and outreach efforts and ultimately result in reduced CVD risk.

Feasibility and challenges of addressing this CQ or CC

Similar studies have been done in this time frame.
There is strong evidence, based on controlled feeding studies, that DASH-style eating patterns can lower blood pressure and improve blood lipids, and thus reduce risk for CVD. Yet, very few individuals regularly follow DASH.

Enabling resource needs.is a challenge in addressing this CQ.

Name of idea submitter and other team members who worked on this idea NHLBI Staff

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Goal 1: Promote Human Health

Achieving accurate and valid dietary assessment for implementing precsion prevention

Combine objective measures and biomarkers of dietary intake to identify dietary deficiencies/excesses that contribute to risk for cardiometabolic diseases. Technological, statistical and methodological advances in diet assessment are increasingly making it possible to identify the nutrients/phytochemicals/ that contribute to risk factor development in individuals and populations. Interdisciplinary studies are needed to... more »

Is this idea a Compelling Question (CQ) or Critical Challenge (CC)? Critical Challenge (CC)

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There is no longer any question that diet, food, eating patterns and overall nutritional status influence health and risk of disease. Over the past fifty years the field of nutrition has grown and become increasingly evidence-based as illustrated by the important work of the US Dietary Guidelines Advisory Committees that are convened every five years to review the new and expanding data relevant to public health. Despite tremendous advances, the field remains handicapped by the absence of accurate objective diet assessment methods that could enhance the recognized limitations and flaws in the existing system. Studies that rely on self-reported recall of dietary intake are inherently limited by cognitive ability, memory, honesty and capacity to provide the details needed to accurately portray a persons nutritional intake. Advances in technology that include metabolomics and other omics, refinements in biomarker measurement and statistical advances such as principal component analyses have been helpful, but most existing studies are limited to one or two of these options, using flawed diet assessment methods and very few days of dietary intake that do not do justice to accurate reflection of nutritional status. Comprehensive studies are needed to combine the available methods and develop approaches that can more precisely identify the relevant factors and thus offer opportunities for improvement.

Feasibility and challenges of addressing this CQ or CC

Successful accomplishment of this challenge will ideally involve Big Data approaches. We are now aware of hundreds of nutrients, micronutrients, phytochemicals and the foods, food groups, eating patterns and environmental factors that all likely contribute to health or risk for disease.
Team science involving nutritionists, biostatisticians, chemists, IT specialists, bioinformatiticians , agricultural specialists, just to name a few will be needed to clearly lay out the key factors and design appropriate approaches to develop the appropriate studies, methodologies and analyses that can address these questions. The time has come!

Name of idea submitter and other team members who worked on this idea Linda Van Horn, PhD, RD

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Goal 2: Reduce Human Disease

What is the optimal management of coronary artery disease in patients with chronic kidney disease

Patients with chronic kidney disease (CKD) have an extremely high risk of death from cardiovascular cause. The prognosis of patients with chronic kidney disease who also have coronary artery disease is worse than certain cancer. While great strides have been made to create awareness about breast cancer, there is paucity of knowledge about the cardiovascular risk of CKD patients among both physicians and patients. Moreover,... more »

Is this idea a Compelling Question (CQ) or Critical Challenge (CC)? Compelling Question (CQ)

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Patients with chronic kidney disease tend to be undertreated (from CV perspective), underrepresented (in clinical trials) and underdiagnosed with less referral for stress testing, even though cardiovascular cause is the leading cause of death in these patients. Patients with chronic kidney disease is a growing cohort and with increase in obesity and diabetes, the prevalence is exploding exponentially. The decision as to what is the best treatment option for patients with coronary artery disease who also have kidney disease- revascularization or medical therapy-is important and can be a paradigm shift in the way we treat such patients

Feasibility and challenges of addressing this CQ or CC

Randomized clinical trials are urgently needed to answer this question.

Name of idea submitter and other team members who worked on this idea Sripal Bangalore

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Goal 3: Advance Translational Research

Culturally Specific Preventative research

There are ample research evidence related factors contributing to obesity,type 2 diabetes, cardiovascular disease.The research grant money is diverted heavily on "novel" topic such as genes.The preventative efforts are the key to tackle the issues.Often times,researchers on cardiovascular prevention find it difficult to add novel ideas to convince the grant reviewers in their application.There are many communities here... more »

Is this idea a Compelling Question (CQ) or Critical Challenge (CC)? Critical Challenge (CC)

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