Showing 1 ideas for tag "combination"

Goal 2: Reduce Human Disease

Combination Cardioprotective Therapy for AMI

Which therapy or combination of therapies to reduce injury from acute myocardial infarction (AMI) will be most efficacious for future clinical trials?

Is this idea a Compelling Question (CQ) or Critical Challenge (CC)? Compelling Question (CQ)

Details on the impact of addressing this CQ or CC

AMI and heart failure continues to be a major cause of morbidity and mortality in the Western world.

Feasibility and challenges of addressing this CQ or CC

Promising cardioprotective candidates are emerging. Additional pre-clinical and clinical research is needed to further investigate these new strategies, alone and in combination, to improve outcomes following AMI.
Numerous studies have implicated various pharmacological and interventional techniques (e.g., adenosine, cyclosporine, postconditioning, and remote ischemic per-conditioning) have been explored.

Name of idea submitter and other team members who worked on this idea NHLBI Staff

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