Impact of each VOC Crisis in patients with sickle cell disease
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Defining critical elements for irreversible myocardial injury
What are the critical mechanisms that account for progression from reversible to irreversible ischemia and reperfusion injury?
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Novel methods to diagnose and treat microvascular ischemia
Microvascular ischemia is common, particularly in the setting of critical illness. We need better ways to evaluate, diagnose and treat these conditions, whether they relate to microvascular myocardial ischemia, as a primary diagnosis of complication of other acute illness, or non-myocardial ischemia during the course of surgery, injury, infection or acute illness.
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Reducing injury following ischemia and reperfusion
What therapeutic strategies can reduce tissue and organ injury caused by total body ischemia and reperfusion?
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Optimal treatment of patients with PAD
What is the optimal treatment of patients with PAD?
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Interaction between organ systems during ischemia and reperfusion
What is the mechanistic interaction of injured organ systems during total body ischemia and reperfusion?
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Molecular effects of ischemia and reperfusion
What is the impact of total body ischemia and reperfusion on coagulation, inflammation, and endothelial function?