Shift from NHLBI guided research to individual investigator initiative
The best way to run the science sponsored by the NIH (or NHLBI) is not to guide it (analogy to running science from ivory tower) but let the investigators decide what is worth pursuing. Get rid of NHLBI-directed research initiative... more »
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Understanding the Genetic & Epigenetic Basis of Congenital Heart Disease?
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Enhanced Pain Research in Sickle Cell Disease
There is a need for more enhanced pain research in order to help improve sickle cell disease patient outcomes and quality of life.
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Mechanism and target identification for cardiovascular disease using database mining and experimental strategies
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A Program of Research in the Prevention of Chronic Heart Failure
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Congential heart defects in diabetic pregnancies: a devastating reality
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A Program of Research in the Prevention of Chronic Heart Failure
There is a need to improve identification and surveillance of persons at risk for heart failure and pathological ventricular remodeling prior to development of clinically overt heart failure.
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Improving patient-centered outcome assessments in HLBS studies
What types of newer patient-centered quality of life assessment tools can be employed in heart, lung, blood and sleep studies so that they can be validated and refined to improve our measurement of quality of life outcomes in populations of interest to NHLBI?
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The missing ingredient in diet and cardiovascular disease prevention research
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The potency and safety of transfusable red blood cells
42 day pre-transfusion storage of RBCs maximizes utilization, while minimizing waste. However, RBCs undergo changes during collection, manipulation and storage that may reduce their potency or safety. Progress in understanding markers that predict transfusion success at the time of collection and with storage remains slow. New technologies... more »
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Clinical Trials and Rare Diseases
Strategies and infrastructure to support clinical trials in rare diseases must go further in the development of critical partnerships with advocacy organizations. These partnerships must be formalized and based on models that help to accelerate the research.
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Towards Collaborative Funding of Clinical Trials
A way for clinical trial investigators to submit ONE application with ONE review and ONE funding decision, and the application would ask for funding from multiple funders (e.g. NHLBI and another IC, NHLBI and PCORI, NHLBI and AHA, NHLBI and CIHR, NHLBI and MRC).