Will sensitivity to the psychological aspects of obesity, including lifestyle priorities and motivations, improve the efficacy of long-term effectiveness of weight loss and obesity prevention interventions?
What information is needed to improve our understanding of individual characteristics and processes that explain or predict dietary intake patterns, initiation or sustained engagement in physical activity, and sedentary behavior so that we can improve treatment matching and identify novel targets for more efficacious individual- and population-level approaches for weight management?
For patients with obesity and medical comorbidities, what is the optimal approach utilizing multiple therapies (low calorie structured diet, intensive lifestyle, weight loss medications) in combination to optimize weight loss?
What is the basis for relative resistance or vulnerabilities to obesity or related adverse health effects observed in various segments of population?
What are the specific contributors of obesity that lead to chronic positive energy balance and surplus energy storage?