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Goal 3: Advance Translational Research

Implementation Research to Improve Global Availability of Safe Blood Transfusions

What well-developed principles and lessons learned can be employed to improve the safety and availability of blood transfusions in developing countries?

The WHO Global Status Report 2013, many research reports, and a recent assessment of burdens of transfusion transmissible infections with HIV, HBV and HCV identified several critical challenges: 1) Significant proportions of blood collections in a large number of countries... more »

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7 net votes
20 up votes
13 down votes
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(@chriscage) kudos icon +

Goal 3: Advance Translational Research

treating sleep apnea without a nose or facial mask

I am lucky to still be alive. I developed heart failure at 41. I turn 60 this month. For the last five years, doctors have tried to get me on a CPAP. I have told them that I'd rather die. I have absolutely no interest in sleeping with a darth vader mask or some strange thing strapped to my nose. Furthermore I had sinus surgery 30 years ago that only partiallly cleared my sinus passage. So forcing air up my nose is very... more »

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26 net votes
43 up votes
17 down votes
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Goal 3: Advance Translational Research

High cost, high risk and unclear benefits of current COPD care

Challenge the unspoken of high cost, high risk and unclear benefits of current COPD care

a. PRCT of lung transplantation vs. optimized medical care
b. Noninvasive ventilation for treatment of chronic severe respiratory failure
c. Chronic combined vs. de-escalation of chronic bronchodilator therapy to as needed for GOLD stages III-IV
d. Self management programs in COPD
e. Telemedicine in outpatient management of severe... more »

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2 net votes
2 up votes
0 down votes
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Goal 3: Advance Translational Research

Obesity in special needs populations: Congenital heart disease

What are effective prevention and treatment strategies for populations with special needs, such as those with congenital heart disease, Down syndrome and preterm-born, to maintain a healthy weight?

Are there successful strategies derived from "normal" populations that could be effectively applied to these populations?

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-24 net votes
12 up votes
36 down votes
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(@wheeze) kudos icon +

Goal 3: Advance Translational Research

Clinical Trial Methodology

As the current chair of the Research and Training Division, I would like to convey that the AAAAI membership would like the NHLBI to consider the following in the development of its strategic plan:

 

Are the current methodologies for clinical trials still the best practices for conducting efficient clinical trials?

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2 net votes
15 up votes
13 down votes
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Goal 3: Advance Translational Research

Leveraging Networks of Federally Qualified Healthcare Centers

How best do we leverage the existing Federally Qualified Healthcare Center’s (FQHC) infrastructure to study T4 Implementation Research for heart, lung, blood, sleep diseases and conditions among high risk and vulnerable populations?

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-14 net votes
7 up votes
21 down votes
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(@ewong0) kudos icon +

Goal 3: Advance Translational Research

Novel Cell Apheresis Technologies to Treat Hematologic Diseases

Current FDA approved apheresis technology uses elutriation/centrifugation or filtration separation techniques to remove pathologic cellular and/or plasma elements. Currently these techniques are non-specific, limited by inefficient removal kinetics and often require considerable blood product exposure. Despite tremendous improvement in our understanding of the pathophysiology of a variety of disease, our ability to... more »

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118 net votes
139 up votes
21 down votes
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Goal 3: Advance Translational Research

Leveraging big data for T4 translation research

What approaches can help leverage the emerging big data in health and health care for observational and interventional implementation research in heart, lung, blood, sleep diseases?

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16 up votes
16 down votes
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