The critical challenges to effective early translation of discovery science experienced by the investigator community include:
1. The need for translational skills development, training and guidance
2. Need for... more »
Can new advances in allogeneic blood or marrow transplantation (BMT) make the procedure a safe and universally available therapeutic strategy for treating non-malignant blood and immune disorders such as sickle cell anemia, thalassemia, aplastic anemia, and severe combined immune deficiency?
Translational research supporting stem cell therapy for cardiovascular disease, including: core laboratories for preclinical IND-enabling studies (e.g., PACT), and clinical trials networks for evaluating promising new treatments (e.g., CCTRN).
What are practical point-of-care diagnostic biomarkers that could be used for assessment of sleep/circadian health, sleep disorders, and the risk of sleep-related heart, lung, and blood diseases?